SCHEMBL1494520

SCHEMBL1494520

CCCCCCCCCCCCOc1[c]nccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.40
TLR8 Q9NR97 2/20 0.40
NR5A1 Q13285 1/20 0.40
TSHR P16473 2/20 0.39
NFKB1 P19838 3/20 0.39
NFKB2 Q00653 3/20 0.39
RELA Q04206 3/20 0.39
MAPT P10636 2/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
FAAH O00519 1/20 0.39
MGLL Q99685 1/20 0.39
LTA4H P09960 1/20 0.39
PDE5A O76074 1/20 0.37
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1494604 1.00 LMNA (0.40) LMNATLR8NR5A1TSHRNFKB1
SCHEMBL1494434 1.00 LMNA (0.40) LMNATLR8NR5A1TSHRNFKB1
SCHEMBL1494289 1.00 LMNA (0.40) LMNATLR8NR5A1TSHRNFKB1
SCHEMBL1494447 1.00 LMNA (0.40) LMNATLR8NR5A1TSHRNFKB1
SCHEMBL1494281 1.00 LMNA (0.40) LMNATLR8NR5A1TSHRNFKB1
SCHEMBL1494545 0.98 LTA4H (0.40) LMNATLR8NR5A1TSHRNFKB1
SCHEMBL1494205 0.93 CYP2D6 (0.42) LMNATLR8TSHRMAPTNPC1
SCHEMBL1494518 0.87 NPC1 (0.38) LMNATLR8TSHRMAPTNPC1
SCHEMBL1036211 0.80
SCHEMBL933769 0.79 LSS (0.44) SMN1; SMN2KDM4ECYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9048442-B2 Composition containing a metal complex and organic compound, and light-emitting element using said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-06-02 US disclosed
EP-2305772-B1 COMPOSITION CONTAINING A METAL COMPLEX AND ORGANIC COMPOUND, AND LIGHT EMITTING ELEMENT USING SAID COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-05-20 EP disclosed
US-8592544-B2 Polymeric compound containing metal complex residue and element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-11-26 US disclosed
US-20110124808-A1 POLYMERIC COMPOUND CONTAINING METAL COMPLEX RESIDUE AND ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-26 US disclosed
US-20110114890-A1 COMPOSITION CONTAINING A METAL COMPLEX AND ORGANIC COMPOUND, AND LIGHT-EMITTING ELEMENT USING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-19 US disclosed
EP-2305772-A1 COMPOSITION CONTAINING A METAL COMPLEX AND ORGANIC COMPOUND, AND LIGHT EMITTING ELEMENT USING SAID COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-04-06 EP disclosed
EP-2298828-A1 POLYMERIC COMPOUND CONTAINING METAL COMPLEX RESIDUE AND ELEMENT COMPRISING SAME Sumitomo Chemical Company, Limited (JP) 2011-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124808-A1 POLYMERIC COMPOUND CONTAINING METAL COMPLEX RESIDUE AND ELEMENT COMPRISING SAME ZRANB2, ZKSCAN2, SLC39A3 LMNA 4766/4885TLR8 2477/4885NR5A1 1888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.