SCHEMBL14947362

SCHEMBL14947362

CCOC(=O)CCCN(CCCC(=O)OCC)c1ccc(C)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
ALOX5 P09917 1/20 0.48
POLB P06746 1/20 0.46
RAB9A P51151 1/20 0.46
CYP1A2 P05177 2/20 0.44
CYP4F2 P78329 3/20 0.43
CYP4A11 Q02928 3/20 0.43
ALDH1A1 P00352 3/20 0.43
PPARG P37231 1/20 0.43
CYP3A4 P08684 2/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
CYP4Z1 Q86W10 2/20 0.41
CYP4F11 Q9HBI6 1/20 0.41
CYP4F12 Q9HCS2 1/20 0.41
HTT P42858 2/20 0.41
ABL1 P00519 1/20 0.41
RIN1 Q13671 1/20 0.41
NR1I2 O75469 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8911435 0.90 SMN1; SMN2 (0.54) SMN1; SMN2ALOX5POLBRAB9ACYP1A2
SCHEMBL13086504 0.89 SMN1; SMN2 (0.43) SMN1; SMN2ALOX5POLBRAB9ACYP1A2
SCHEMBL14570550 0.87 SMN1; SMN2 (0.51) SMN1; SMN2ALOX5POLBRAB9ACYP1A2
SCHEMBL2762361 0.87 SMN1; SMN2 (0.63) SMN1; SMN2ALOX5CYP1A2CYP4F2CYP4A11
SCHEMBL13084328 0.83 SMN1; SMN2 (0.58) SMN1; SMN2ALOX5CYP1A2CYP4F2CYP4A11
SCHEMBL23692522 0.82 SMN1; SMN2 (0.54) SMN1; SMN2ALOX5POLBRAB9ACYP1A2
SCHEMBL16212493 0.82 SMN1; SMN2 (0.50) SMN1; SMN2ALOX5RAB9ACYP1A2CYP4F2
SCHEMBL532276 0.82 SMN1; SMN2 (0.57) SMN1; SMN2ALOX5CYP1A2CYP4F2CYP4A11
SCHEMBL2498213 0.81 SMN1; SMN2 (0.60) SMN1; SMN2ALOX5CYP1A2CYP4F2CYP4A11
SCHEMBL1226479 0.81 PPARG (0.49) SMN1; SMN2ALOX5POLBCYP1A2CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130118570-A1 DYE FOR PHOTOELECTRIC CONVERSION, SEMICONDUCTOR ELECTRODE, PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND NOVEL PYRROLINE-BASED COMPOUND NEC CORPORATION (JP) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130118570-A1 DYE FOR PHOTOELECTRIC CONVERSION, SEMICONDUCTOR ELECTRODE, PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND NOVEL PYRROLINE-BASED COMPOUND SCO2, PYCR1, CRY1 SMN1; SMN2 4148/4885ALOX5 3444/4885POLB 2241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.