Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 1.00 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.69 |
| ▸ | CTSL | P07711 | 2/20 | 0.69 |
| ▸ | CTSB | P07858 | 2/20 | 0.69 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | KRAS | P01116 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527372 | 1.00 | ABCB1 (1.00) | ABCB1CAPN1CTSLCTSBTNFRSF1A | |
| SCHEMBL14947394 | 0.90 | ABCB1 (0.81) | ABCB1CAPN1CTSLCTSBTNFRSF1A | |
| SCHEMBL14947391 | 0.89 | ABCB1 (1.00) | ABCB1CAPN1CTSLCTSBNPC1 | |
| SCHEMBL527576 | 0.87 | ABCB1 (1.00) | ABCB1CAPN1CTSLCTSBTNFRSF1A | |
| SCHEMBL14947392 | 0.87 | ABCB1 (1.00) | ABCB1CAPN1CTSLCTSBTNFRSF1A | |
| SCHEMBL14947393 | 0.86 | TNFRSF1A (0.82) | ABCB1TNFRSF1AABCG2KRAS | |
| SCHEMBL31059027 | 0.81 | ABCB1 (0.67) | ABCB1TNFRSF1ANPC1LMNAMAPT | |
| SCHEMBL14947395 | 0.79 | ABCB1 (0.70) | ABCB1TNFRSF1AABCG2BCHEMAOB | |
| SCHEMBL12484518 | 0.78 | TNFRSF1A (1.00) | ABCB1TNFRSF1AABCG2KRAS | |
| SCHEMBL12484514 | 0.78 | TNFRSF1A (1.00) | ABCB1TNFRSF1AABCG2KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MEDIZINISCHE UNIVERSITAT WIEN (AT) | 2013-05-16 | — | — | US | disclosed |
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MEDIZINISCHE UNIVERSITAT WIEN (AT) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MALT1, VHL, ETV6 | ABCB1 19/4885CAPN1 4720/4885CTSL 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.