Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.81 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.64 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.59 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | KRAS | P01116 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527372 | 0.90 | ABCB1 (1.00) | ABCB1ABCG2TNFRSF1ACAPN1CTSL | |
| SCHEMBL14947390 | 0.90 | ABCB1 (1.00) | ABCB1ABCG2TNFRSF1ACAPN1CTSL | |
| SCHEMBL14947392 | 0.83 | ABCB1 (1.00) | ABCB1ABCG2TNFRSF1ACAPN1CTSL | |
| SCHEMBL527576 | 0.83 | ABCB1 (1.00) | ABCB1ABCG2TNFRSF1ACAPN1CTSL | |
| SCHEMBL14947393 | 0.82 | TNFRSF1A (0.82) | ABCB1ABCG2TNFRSF1AKRAS | |
| SCHEMBL14947391 | 0.79 | ABCB1 (1.00) | ABCB1CAPN1CTSLCTSBMAOB | |
| SCHEMBL30504731 | 0.77 | ABCG2 (0.73) | ABCB1ABCG2TNFRSF1AKRASLMNA | |
| SCHEMBL14947395 | 0.75 | ABCB1 (0.70) | ABCB1ABCG2TNFRSF1AMAOBKRAS | |
| SCHEMBL14947399 | 0.75 | CAPN1 (0.59) | ABCB1ABCG2CAPN1CTSLCTSB | |
| SCHEMBL12484518 | 0.74 | TNFRSF1A (1.00) | ABCB1ABCG2TNFRSF1AKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MEDIZINISCHE UNIVERSITAT WIEN (AT) | 2013-05-16 | — | — | US | disclosed |
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MEDIZINISCHE UNIVERSITAT WIEN (AT) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MALT1, VHL, ETV6 | ABCB1 19/4885ABCG2 202/4885TNFRSF1A 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.