Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 1.00 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527576 | 1.00 | ABCB1 (1.00) | ABCB1TNFRSF1ACAPN1CTSLCTSB | |
| SCHEMBL527372 | 0.87 | ABCB1 (1.00) | ABCB1TNFRSF1ACAPN1CTSLCTSB | |
| SCHEMBL14947390 | 0.87 | ABCB1 (1.00) | ABCB1TNFRSF1ACAPN1CTSLCTSB | |
| SCHEMBL14947394 | 0.83 | ABCB1 (0.81) | ABCB1TNFRSF1ACAPN1CTSLCTSB | |
| SCHEMBL14947393 | 0.80 | TNFRSF1A (0.82) | ABCB1TNFRSF1AABCG2KRASTUBB1 | |
| SCHEMBL14947391 | 0.77 | ABCB1 (1.00) | ABCB1CAPN1CTSLCTSBNPC1 | |
| SCHEMBL15286194 | 0.76 | ABCB1 (0.65) | ABCB1TNFRSF1ATUBB1TUBB4ATUBB | |
| SCHEMBL15285833 | 0.75 | ABCB1 (0.64) | ABCB1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL14947395 | 0.73 | ABCB1 (0.70) | ABCB1TNFRSF1AABCG2KRASTUBB1 | |
| SCHEMBL12484518 | 0.72 | TNFRSF1A (1.00) | ABCB1TNFRSF1AABCG2KRASTUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MEDIZINISCHE UNIVERSITAT WIEN (AT) | 2013-05-16 | — | — | US | disclosed |
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MEDIZINISCHE UNIVERSITAT WIEN (AT) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MALT1, VHL, ETV6 | ABCB1 19/4885TNFRSF1A 2195/4885CAPN1 4720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.