Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92227 | 0.86 | NR1I2 (0.55) | CYP3A4SMN1; SMN2NR1I2MAPTTSHR | |
| SCHEMBL14950986 | 0.85 | APP (0.54) | CYP3A4SMN1; SMN2NR1I2MAPTTSHR | |
| SCHEMBL11793591 | 0.83 | ALDH1A1 (0.48) | CYP3A4SMN1; SMN2MAPTTSHRMAPK1 | |
| SCHEMBL20123355 | 0.75 | ALDH1A1 (0.66) | CYP3A4SMN1; SMN2MAPTTSHRMAPK1 | |
| SCHEMBL21556921 | 0.73 | APP (0.56) | CYP3A4MAPTTSHRMAPK1HTT | |
| SCHEMBL4545012 | 0.73 | ALDH1A1 (0.45) | CYP3A4SMN1; SMN2MAPTTSHRMAPK1 | |
| SCHEMBL14173686 | 0.72 | NR1I2 (0.53) | CYP3A4SMN1; SMN2NR1I2MAPTTSHR | |
| SCHEMBL14948102 | 0.71 | APP (0.51) | CYP3A4SMN1; SMN2NR1I2MAPTTSHR | |
| Alcohol SCHEMBL15135686 | 0.70 | SMN1; SMN2 (0.64) | CYP3A4SMN1; SMN2NR1I2APPALDH1A1 | |
| SCHEMBL7908974 | 0.70 | CYP3A4 (0.59) | CYP3A4SMN1; SMN2NR1I2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160139143-A1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MEDICAL SYSTEMS, INC. | 2016-05-19 | — | — | US | disclosed |
| US-9291597-B2 | Detecting targets using mass tags and mass spectrometry | VENTANA MEDICAL SYSTEMS, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-20130122516-A1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MEDICAL SYSTEMS, INC. | 2013-05-16 | — | — | US | disclosed |