SCHEMBL14948320

SCHEMBL14948320

Cc1cccc(N(c2cccc(C)c2)c2cccc(C[N+](C)(C)C)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
JAK2 O60674 1/20 0.39
HTT P42858 1/20 0.39
PAX8 Q06710 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
IDO1 P14902 2/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37
ACHE P22303 1/20 0.37
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
CETP P11597 1/20 0.35
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948319 0.88 ALDH1A1 (0.41) ALDH1A1KDM4ETDP1CHRNB2CHRNA4
SCHEMBL14948389 0.86 ALDH1A1 (0.55) ALDH1A1KDM4ETDP1HTTCHRNB2
SCHEMBL16187144 0.83 KDM4E (0.54) ALDH1A1KDM4ETDP1TAAR1IDO1
SCHEMBL31658952 0.83 KDM4E (0.54) ALDH1A1KDM4ETDP1TAAR1IDO1
SCHEMBL14948387 0.81 ALDH1A1 (0.41) ALDH1A1KDM4ETDP1TAAR1IDO1
Hydrochloric Acid SCHEMBL30019608 0.81 KDM4E (0.58) ALDH1A1KDM4ETDP1TAAR1IDO1
Hydrochloric Acid SCHEMBL22265015 0.81 KDM4E (0.58) ALDH1A1KDM4ETDP1TAAR1IDO1
Bromide SCHEMBL6257521 0.81 KDM4E (0.52) ALDH1A1KDM4ETDP1TAAR1IDO1
SCHEMBL20030125 0.80 SIGMAR1 (0.43) ALDH1A1RAB9ANPC1JAK2HTT
SCHEMBL14948406 0.80 KDM4E (0.40) ALDH1A1KDM4ETDP1HTTTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed