SCHEMBL14948397

SCHEMBL14948397

CC[N+](CC)(CC)Cc1cc(C)c(N(c2ccccc2)c2ccccc2)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
CYP1A2 P05177 2/20 0.33
CHRNA7 P36544 5/20 0.33
CHRNB4 P30926 4/20 0.33
CHRNA3 P32297 4/20 0.33
MEN1 O00255 2/20 0.33
CYP2D6 P10635 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
TAS2R10 Q9NYW0 1/20 0.33
CHRNB2 P17787 2/20 0.33
CHRNA4 P43681 2/20 0.33
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 3/20 0.31
FAAH O00519 1/20 0.31
PHGDH O43175 1/20 0.31
MGLL Q99685 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948331 0.86 ALDH1A1 (0.33) TSHRALDH1A1CYP2C19
SCHEMBL14948388 0.78 ALDH1A1 (0.43) TSHRCYP1A2CHRNA7CHRNB4CHRNA3
SCHEMBL14948471 0.77 TSHR (0.43) TSHRCYP1A2MEN1CYP2D6KMT2A
SCHEMBL3477723 0.73 CYP1A2 (0.41) TSHRACHECYP1A2MEN1CYP2D6
Benzene SCHEMBL29130108 0.72 KDM4E (0.54) BCHEACHECYP1A2CHRNA7CHRNB4
Hydrogen Sulfide SCHEMBL5998579 0.72 KDM4E (0.54) BCHEACHECYP1A2CHRNA7CHRNB4
SCHEMBL81238 0.72 KDM4E (0.54) BCHEACHECYP1A2CHRNA7CHRNB4
SCHEMBL17928941 0.72 SKP2 (0.46) BCHECYP1A2CYP2D6NPSR1MAPK1
SCHEMBL15854844 0.72 SKP2 (0.46) BCHECYP1A2CYP2D6NPSR1MAPK1
SCHEMBL1115692 0.71 L3MBTL1 (0.43) TSHRACHECYP1A2MEN1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed