SCHEMBL14948426

SCHEMBL14948426

Cc1ccc(N(c2ccc(C)cc2)c2ccc(COS(=O)(=O)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA9 Q16790 1/20 0.53
CNR2 P34972 14/20 0.46
CNR1 P21554 10/20 0.44
MAPT P10636 1/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
HCRTR2 O43614 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18843583 1.00 CA1 (0.53) CA1CA2CA9CNR2CNR1
SCHEMBL14948429 0.92 CA1 (0.49) CA1CA2CA9CNR2CNR1
SCHEMBL8052920 0.90 CA2 (0.63) CA1CA2CA9MAPT
SCHEMBL6859827 0.90 CA2 (0.63) CA1CA2CA9MAPT
SCHEMBL16667873 0.89 CNR2 (0.52) CA1CA2CA9CNR2CNR1
SCHEMBL18843570 0.87 CA1 (0.41) CA1CA2CA9CNR2CNR1
SCHEMBL18843569 0.87 CA1 (0.41) CA1CA2CA9CNR2CNR1
SCHEMBL5870520 0.87 CA2 (0.56) CA1CA2CA9MAPTHCRTR2
SCHEMBL18843477 0.84 KEAP1 (0.41) CA1CA2CA9CNR2CNR1
SCHEMBL7890851 0.83 CA2 (0.56) CA1CA2CA9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9829810-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method for producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2017-11-28 US disclosed
US-20170131646-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2017-05-11 US disclosed
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed