SCHEMBL14948438

SCHEMBL14948438

Cc1cccc2c(N(c3cccc4c(C)cccc34)c3cccc4c(CBr)cccc34)cccc12

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.45
CYP2A6 P11509 3/20 0.45
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.32
AHR P35869 1/20 0.31
CYP2D6 P10635 2/20 0.31
CYP2C19 P33261 2/20 0.31
CYP3A4 P08684 1/20 0.31
SOS2 Q07890 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10900222 0.87 CYP1A2 (0.59) CYP1A2CYP2A6ALDH1A1CYP2D6CYP2C19
SCHEMBL20631333 0.81 CYP1A2 (0.50) CYP1A2CYP2A6ALDH1A1CYP2D6CYP2C19
SCHEMBL14948472 0.81 CYP2D6 (0.42) CYP1A2ALDH1A1CYP2D6CYP2C19
SCHEMBL14948324 0.80 CYP1A2 (0.42) CYP1A2CYP2A6ALDH1A1GAACYP2D6
SCHEMBL31532953 0.75 CYP1A2 (0.59) CYP1A2CYP2A6ALDH1A1CYP2D6CYP2C19
SCHEMBL2141182 0.74 GABRA1 (0.38) CYP1A2CYP2A6ALDH1A1CYP2D6CYP2C19
SCHEMBL10053554 0.71 CYP1A2 (0.65) CYP1A2CYP2A6ALDH1A1CYP3A4
SCHEMBL13367583 0.71 CYP1A2 (0.52) CYP1A2CYP2A6ALDH1A1GAAAHR
SCHEMBL12744236 0.69 CYP2A6 (0.54) CYP1A2CYP2A6ALDH1A1CYP2D6CYP2C19
SCHEMBL469267 0.69 CYP1A2 (0.62) CYP1A2CYP2A6ALDH1A1GAACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed