SCHEMBL469267

SCHEMBL469267

Cc1cccc2c(N(C)C)cccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.62
CYP2A6 P11509 3/20 0.62
CHEK1 O14757 1/20 0.54
NEK2 P51955 1/20 0.54
LIMK1 P53667 1/20 0.54
DYRK1A Q13627 1/20 0.54
CLK4 Q9HAZ1 1/20 0.54
CA2 P00918 1/20 0.50
EP300 Q09472 1/20 0.47
KAT2B Q92831 1/20 0.47
KAT8 Q9H7Z6 1/20 0.47
ALDH1A1 P00352 2/20 0.46
GAA P10253 4/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPT P10636 2/20 0.44
CYP2C19 P33261 1/20 0.44
HTT P42858 1/20 0.44
HIF1A Q16665 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29862158 1.00 CYP1A2 (0.62) CYP1A2CYP2A6CHEK1NEK2LIMK1
SCHEMBL8720110 0.87 CHEK1 (0.65) CYP1A2CHEK1NEK2LIMK1DYRK1A
SCHEMBL29862285 0.86 CYP1A2 (0.62) CYP1A2CYP2A6CHEK1NEK2LIMK1
SCHEMBL1755244 0.86 CYP1A2 (0.62) CYP1A2CYP2A6CHEK1NEK2LIMK1
SCHEMBL424167 0.79 CYP1A2 (1.00) CYP1A2CYP2A6CA2ALDH1A1TDP1
SCHEMBL29463284 0.79 CYP1A2 (1.00) CYP1A2CYP2A6CA2ALDH1A1TDP1
SCHEMBL14959260 0.79 CYP1A2 (0.52) CYP1A2CYP2A6CHEK1NEK2LIMK1
SCHEMBL29862298 0.77 MEN1 (0.47) CYP1A2CYP2A6CHEK1NEK2LIMK1
SCHEMBL8990307 0.76 CHEK1 (0.73) CYP1A2CHEK1NEK2LIMK1DYRK1A
SCHEMBL29919884 0.76 CHEK1 (0.73) CYP1A2CHEK1NEK2LIMK1DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12510529-B2 Method for determining authenticity and adulteration of marked petroleum hydrocarbons SICPA HOLDING SA (CH) 2025-12-30 US disclosed
EP-4069806-B1 METHOD OF MARKING A PETROLEUM HYDROCARBON SICPA HOLDING SA (CH) 2025-04-16 EP disclosed
US-20240327736-A1 METHOD OF MARKING A PETROLEUM HYDROCARBON SICPA HOLDING SA (CH) 2024-10-03 US disclosed
US-12031098-B2 Method of marking a petroleum hydrocarbon SICPA HOLDING SA (CH) 2024-07-09 US disclosed
US-20230312498-A1 NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS UNIVERSITY OF MARYLAND, BALTIMORE 2023-10-05 US disclosed
EP-4069807-B1 METHOD FOR DETERMINING AUTHENTICITY AND ADULTERATION OF MARKED PETROLEUM HYDROCARBONS SICPA HOLDING SA (CH) 2023-10-04 EP disclosed
EP-3469088-B1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS CODEXIS INC (US) 2023-09-06 EP disclosed
US-11718595-B2 Non-ATP/catalytic site p38 Mitogen Activated Protein Kinase inhibitors UNIVERSITY OF MARYLAND, BALTIMORE (US) 2023-08-08 US disclosed
US-20230140941-A1 NON-ATP/CATALYTIC SITE P38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2023-05-11 US disclosed
US-20230103579-A1 METHOD FOR DETERMINING AUTHENTICITY AND ADULTERATION OF MARKED PETROLEUM HYDROCARBONS SICPA HOLDING SA (CH) 2023-04-06 US disclosed
US-7173035-B2 Arylsulfonamide compounds BIOVITRUM AB (SE) 2007-02-06 US disclosed
US-7173035-B2 Arylsulfonamide compounds BIOVITRUM AB (SE) 2007-02-06 US disclosed
US-7169925-B2 Indole derivatives as interleukin-4 gene expression inhibitors AVENTIS PHARMACEUTICALS INC. (US) 2007-01-30 US disclosed
US-7169925-B2 Indole derivatives as interleukin-4 gene expression inhibitors AVENTIS PHARMACEUTICALS INC. (US) 2007-01-30 US disclosed
US-7166603-B2 Dihydropyrimidone inhibitors of calcium channel function BRISTOL-MYERS SQUIBB CO. (US) 2007-01-23 US disclosed
US-20070009597-A1 Active substance combination comprising a compound with npy receptor affinity and a compound with 5-ht6 receptor affinity LABORATORIOS DEL DR. ESTEVE S.A. (ES) 2007-01-11 US disclosed
US-7157454-B2 Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same SANOFI-AVENTIS (FR) 2007-01-02 US disclosed
US-7157454-B2 Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same SANOFI-AVENTIS (FR) 2007-01-02 US disclosed
WO-2006097293-A2 COMBINATION OF A STEROID SULFATASE INHIBITOR AND AN ASCOMYCIN NOVARTIS AG (CH) 2006-09-21 WO disclosed
WO-2005009392-A2 DIHYDROPYRIMIDONE INHIBITORS OF CALCIUM CHANNEL FUNCTION BRISTOL-MYERS SQUIBB COMPANY (US) 2005-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230140941-A1 NON-ATP/CATALYTIC SITE P38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS MAPK1, MAPK8, MAPK4 CYP1A2 3599/4885CYP2A6 3683/4885CHEK1 688/4885
US-20230312498-A1 NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS MAPK1, MAPK8, MAPK4 CYP1A2 3491/4885CYP2A6 4026/4885CHEK1 639/4885
US-12510529-B2 Method for determining authenticity and adulteration of marked petroleum hydrocarbons CYP4A11, CYP11B1, CYP11A1 CYP1A2 57/4885CYP2A6 75/4885CHEK1 3332/4885
US-11718595-B2 Non-ATP/catalytic site p38 Mitogen Activated Protein Kinase inhibitors MAPK1, MAPK8, MAPK4 CYP1A2 3491/4885CYP2A6 4026/4885CHEK1 639/4885
US-20070009597-A1 Active substance combination comprising a compound with npy receptor affinity and a compound with 5-ht6 receptor affinity NPY5R, HTR6, NPY2R CYP1A2 3453/4885CYP2A6 1150/4885CHEK1 4861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.