SCHEMBL14948442

SCHEMBL14948442

Cc1ccc(N(c2ccc(C)cc2)c2c(C)cc(CBr)cc2C)cc1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.36
S100B P04271 1/20 0.35
IDO1 P14902 1/20 0.31
CNR2 P34972 3/20 0.31
ACHE P22303 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SKP2 Q13309 1/20 0.31
GSK3B P49841 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.31
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948471 0.85 TSHR (0.43) ALDH1A1TSHRCYP2C19S100BCNR2
SCHEMBL14948424 0.79 ALDH1A1 (0.42) ALDH1A1TSHRCYP2C19IDO1CNR2
SCHEMBL682063 0.79 ALDH1A1 (0.46) ALDH1A1TSHRCYP2C19S100BACHE
SCHEMBL12018763 0.79 ALDH1A1 (0.46) ALDH1A1TSHRCYP2C19S100BACHE
SCHEMBL12593358 0.78 SKP2 (0.47) ALDH1A1TSHRCYP2C19CNR2SKP2
SCHEMBL12313660 0.78 SKP2 (0.47) ALDH1A1TSHRCYP2C19CNR2SKP2
SCHEMBL15854847 0.78 SKP2 (0.47) ALDH1A1TSHRCYP2C19CNR2SKP2
SCHEMBL13308448 0.77 CYP1A2 (0.42) ALDH1A1TSHRCYP2C19IDO1
SCHEMBL14948331 0.77 ALDH1A1 (0.33) ALDH1A1TSHRCYP2C19
SCHEMBL12313694 0.77 SKP2 (0.46) CYP2C19CNR2SKP2RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed