SCHEMBL14948475

SCHEMBL14948475

BrCc1ccc2c(c1)c1ccccc1n2-c1ccc(Br)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
TP53 P04637 2/20 0.47
KDM4E B2RXH2 2/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TSPO P30536 3/20 0.38
DNM1 Q05193 2/20 0.37
PTPN1 P18031 2/20 0.36
POLB P06746 2/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.35
MEN1 O00255 1/20 0.35
RAD52 P43351 1/20 0.35
KMT2A Q03164 1/20 0.35
F2 P00734 1/20 0.34
F10 P00742 1/20 0.34
PRSS1 P07477 1/20 0.34
CXCR3 P49682 1/20 0.33
HDAC4 P56524 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948582 0.87 MAPT (0.46) MAPTTP53KDM4EATML3MBTL1
SCHEMBL782608 0.84 L3MBTL1 (0.55) MAPTTP53KDM4EATML3MBTL1
SCHEMBL29842645 0.84 L3MBTL1 (0.55) MAPTTP53KDM4EATML3MBTL1
SCHEMBL9881173 0.84 KDM4E (0.55) MAPTTP53KDM4EATML3MBTL1
SCHEMBL29357559 0.84 KDM4E (0.55) MAPTTP53KDM4EATML3MBTL1
SCHEMBL22698769 0.84 KDM4E (0.53) MAPTTP53KDM4EATML3MBTL1
SCHEMBL38818 0.84 L3MBTL1 (0.59) MAPTKDM4EATML3MBTL1PTPN1
SCHEMBL27951951 0.82 KDM4E (0.57) MAPTTP53KDM4EATML3MBTL1
SCHEMBL29400116 0.82 KDM4E (0.67) KDM4EATML3MBTL1DNM1PTPN1
SCHEMBL262160 0.82 KDM4E (0.67) KDM4EATML3MBTL1DNM1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed