SCHEMBL782608

SCHEMBL782608

Brc1ccc(-n2c3ccccc3c3cc(Br)ccc32)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ATM Q13315 1/20 0.55
TSPO P30536 2/20 0.44
MEN1 O00255 1/20 0.43
RAD52 P43351 1/20 0.43
KMT2A Q03164 1/20 0.43
HTT P42858 1/20 0.41
MAPT P10636 2/20 0.40
TP53 P04637 1/20 0.40
RXFP1 Q9HBX9 2/20 0.38
ALDH1A1 P00352 1/20 0.38
DNM1 Q05193 2/20 0.38
HDAC4 P56524 1/20 0.38
ACHE P22303 2/20 0.37
BCHE P06276 1/20 0.37
LIG1 P18858 1/20 0.36
KRAS P01116 1/20 0.36
PTPN1 P18031 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29842645 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL14913074 0.93 L3MBTL1 (0.52) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL26218475 0.93 L3MBTL1 (0.52) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL30040723 0.93 L3MBTL1 (0.52) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL9881173 0.93 KDM4E (0.55) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL29357559 0.93 KDM4E (0.55) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL261514 0.93 L3MBTL1 (0.67) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL30032326 0.93 L3MBTL1 (0.67) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL28129746 0.93 L3MBTL1 (0.67) L3MBTL1KDM4EATMTSPOMEN1
SCHEMBL29993566 0.93 L3MBTL1 (0.67) L3MBTL1KDM4EATMTSPOMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114914382-A Application of low-temperature short-time thermal crosslinking material as hole transport material, hole transport layer and PhOLED device 滇西应用技术大学 2022-08-16 CN claimed
CN-114914382-A Application of low-temperature short-time thermal crosslinking material as hole transport material, hole transport layer and PhOLED device 滇西应用技术大学 2022-08-16 CN disclosed
US-20220069225-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING THE SAME ROHM & HAAS ELECT MAT (US) 2022-03-03 US disclosed
US-20210210691-A1 POLYMERIC LAYER AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME. DOW GLOBAL TECHNOLOGIES LLC (US) 2021-07-08 US disclosed
US-10454036-B2 Polymeric charge transfer layer and organic electronic device containing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2019-10-22 US disclosed
US-10256410-B2 Compositions comprising oxygen substituted benzocyclobutenes and dienophiles, and electronic devices containing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-09 US disclosed
US-20180226584-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-08-09 US disclosed
US-20180226584-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-08-09 US disclosed
US-9793485-B2 Benzocyclobutenes derived compositions, and electronic devices containing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-17 US disclosed
US-9793485-B2 Benzocyclobutenes derived compositions, and electronic devices containing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-17 US disclosed
WO-2016028902-A1 COMPOSITIONS CONTAINING BENZOCYCLOBUTENE SUBSTITUTED CARBAZOLES, AND ELECTRONIC DEVICES CONTAINING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2016-02-25 WO disclosed
WO-2016028902-A1 COMPOSITIONS CONTAINING BENZOCYCLOBUTENE SUBSTITUTED CARBAZOLES, AND ELECTRONIC DEVICES CONTAINING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2016-02-25 WO disclosed
US-20150053940-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-02-26 US disclosed
US-20150053940-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-02-26 US disclosed
US-20150053940-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-02-26 US disclosed
EP-2436751-B1 CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME SK CHEMICALS CO LTD (KR) 2015-01-07 EP disclosed
CN-102439111-A Carbazole-based phosphine oxide compound and organic electroluminescent device comprising the same UNIV DANKOOK IACF 2012-05-02 CN disclosed
US-20120068168-A1 CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) 2012-03-22 US disclosed
US-20120068168-A1 CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) 2012-03-22 US disclosed
US-20120068168-A1 CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10454036-B2 Polymeric charge transfer layer and organic electronic device containing the same CLTB, CYBA, L1CAM L3MBTL1 1572/4885KDM4E 1637/4885ATM 3914/4885
US-20180226584-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING THE SAME CLTB, CYBA, L1CAM L3MBTL1 1572/4885KDM4E 1637/4885ATM 3914/4885
US-20120068168-A1 CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME INPP5B, EZH2, PLCB3 L3MBTL1 1822/4885KDM4E 1186/4885ATM 3758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.