Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5356293 | 0.82 | NOTUM (1.00) | NOTUMNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL6527881 | 0.82 | NOTUM (0.70) | NOTUMNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL31049642 | 0.82 | NOTUM (0.70) | NOTUMNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL26232436 | 0.82 | NPC1 (0.73) | NOTUMNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL2107628 | 0.82 | NPC1 (0.64) | NOTUMNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL28912728 | 0.82 | SIRT2 (0.71) | NOTUMNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL17595755 | 0.81 | NOTUM (1.00) | NOTUMNPC1RAB9ASMN1; SMN2S1PR1 | |
| SCHEMBL6504714 | 0.81 | S1PR1 (0.65) | NOTUMSIRT2HDAC8HDAC1HDAC2 | |
| SCHEMBL4522502 | 0.80 | NOTUM (0.71) | NOTUMNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL6528506 | 0.79 | NOTUM (0.66) | NOTUMNPC1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | NOTUM 1461/4885NPC1 4803/4885HTT 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.