SCHEMBL14949153

SCHEMBL14949153

Cc1ccc(C)c(Cc2ccc(O[C@@H]3CCOC3)cc2)c1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 9/20 0.46
SLC5A1 P13866 6/20 0.46
ADAMTS4 O75173 1/20 0.39
MMP13 P45452 1/20 0.39
SYK P43405 1/20 0.37
ACACB O00763 2/20 0.36
FFAR1 O14842 1/20 0.36
PDE4D Q08499 1/20 0.35
HRH3 Q9Y5N1 2/20 0.35
CHRM1 P11229 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15682904 1.00 SLC5A2 (0.46) SLC5A2SLC5A1ADAMTS4MMP13SYK
SCHEMBL14949125 1.00 SLC5A2 (0.46) SLC5A2SLC5A1ADAMTS4MMP13SYK
SCHEMBL14949150 0.88 SLC5A2 (0.59) SLC5A2SLC5A1HRH3
SCHEMBL17859644 0.88 SLC5A2 (0.59) SLC5A2SLC5A1HRH3
SCHEMBL15681530 0.86 SLC5A2 (0.43) SLC5A2SLC5A1ACACBFFAR1PDE4D
SCHEMBL19019428 0.80 SLC5A2 (0.44) SLC5A2SLC5A1PDE4D
SCHEMBL19019426 0.80 SLC5A2 (0.44) SLC5A2SLC5A1PDE4D
SCHEMBL7760091 0.79 LRRK2 (0.43) SYKACACBHRH3
SCHEMBL21443397 0.79 LRRK2 (0.43) SYKACACBHRH3
SCHEMBL13993826 0.79 LRRK2 (0.43) SYKACACBHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2776449-B1 PROCESS FOR THE PREPARATION OF BETA-C-ARYL GLUCOSIDES SCINOPHARM TAIWAN LTD (TW) 2017-08-02 EP disclosed
US-8952139-B2 Process for the preparation of β-C-aryl glucosides SCINOPHARM TAIWAN, LTD (TW) 2015-02-10 US disclosed
US-20140128595-A1 Process for the Preparation of ß-C-Aryl Glucosides SCINOPHARM TAIWAN, LTD. (TW) 2014-05-08 US disclosed
WO-2013068850-A2 PROCESS FOR THE PREPARATION OF β-C-ARYL GLUCOSIDES SCINOPHARM TAIWAN, LTD. (NA) 2013-05-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140128595-A1 Process for the Preparation of ß-C-Aryl Glucosides SLC5A2, SLC5A1, UGGT1 SLC5A2 1/4885SLC5A1 2/4885ADAMTS4 4537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.