Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 14/20 | 0.44 |
| ▸ | BCL2 | P10415 | 10/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935514 | 0.82 | MCL1 (0.60) | MCL1BCL2BCL2L1PRMT1KDM4E | |
| SCHEMBL28028179 | 0.82 | LTA4H (0.44) | MCL1BCL2BCL2L1PRMT1KDM4E | |
| SCHEMBL28834355 | 0.81 | MCL1 (0.41) | MCL1BCL2BCL2L1PRMT1KDM4E | |
| SCHEMBL29151801 | 0.81 | LTA4H (0.42) | MCL1BCL2BCL2L1PRMT1KDM4E | |
| SCHEMBL14935457 | 0.81 | MCL1 (0.63) | MCL1BCL2BCL2L1PRMT1KDM4E | |
| SCHEMBL15177181 | 0.80 | MCL1 (0.58) | MCL1BCL2BCL2L1PRMT1KDM4E | |
| Bromide SCHEMBL28952170 | 0.80 | LTA4H (0.41) | MCL1BCL2BCL2L1PRMT1KDM4E | |
| SCHEMBL29151807 | 0.80 | MCL1 (0.40) | MCL1BCL2BCL2L1PRMT1KDM4E | |
| SCHEMBL29151803 | 0.80 | MCL1 (0.40) | MCL1BCL2BCL2L1PRMT1KDM4E | |
| Bromide SCHEMBL28834308 | 0.79 | MCL1 (0.39) | MCL1BCL2BCL2L1PRMT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123492-A1 | ACENAPHTHO HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2013-05-16 | — | — | US | disclosed |
| US-20130123492-A1 | ACENAPHTHO HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2013-05-16 | — | — | US | disclosed |
| CN-102321012-A | Acenaphthene heterocyclic compound and application thereof | UNIV DALIAN TECH | 2012-01-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123492-A1 | ACENAPHTHO HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | MCL1, BCL2L1, BCL2 | MCL1 1/4885BCL2 3/4885BCL2L1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.