Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20931107 | 0.83 | ALDH1A1 (0.42) | CYP2C19 | |
| SCHEMBL23717146 | 0.77 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL21782763 | 0.77 | TSHR (0.32) | TSHR | |
| SCHEMBL13543295 | 0.77 | MAPK1 (0.35) | TSHRMAPK1CYP2C19 | |
| SCHEMBL14035478 | 0.77 | MAPK1 (0.35) | TSHRMAPK1CYP2C19 | |
| SCHEMBL17577435 | 0.76 | — | — | |
| SCHEMBL14469851 | 0.74 | — | — | |
| SCHEMBL23135345 | 0.74 | CACNA1F (0.32) | — | |
| SCHEMBL13649896 | 0.73 | ALDH1A1 (0.30) | TSHR | |
| SCHEMBL19261510 | 0.71 | GRIK1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735609-B2 | Bryostatin analogues, synthetic methods and uses | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130123518-A1 | Bryostatin Analogues, Synthetic Methods and Uses | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123518-A1 | Bryostatin Analogues, Synthetic Methods and Uses | MCL1, PBK, BID | TSHR 717/4885MAPK1 3720/4885CYP2C19 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.