Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14949861 | 0.99 | CHRNB2 (0.64) | CHRNB2CHRNA4 | |
| SCHEMBL3361284 | 0.91 | CHRNB2 (0.61) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3357412 | 0.90 | CHRNB2 (0.60) | CHRNB2CHRNA4 | |
| SCHEMBL2185714 | 0.87 | CHRNB2 (0.50) | CHRNB2CHRNA4 | |
| SCHEMBL7921214 | 0.87 | CHRNB2 (0.56) | CHRNB2CHRNA4 | |
| SCHEMBL7927942 | 0.85 | CHRNB2 (0.55) | CHRNB2CHRNA4 | |
| SCHEMBL3358357 | 0.83 | CHRNB2 (0.64) | CHRNB2CHRNA4 | |
| SCHEMBL3358669 | 0.82 | CHRNB2 (0.69) | CHRNB2CHRNA4 | |
| SCHEMBL3359336 | 0.82 | CHRNB2 (0.69) | CHRNB2CHRNA4 | |
| SCHEMBL13307518 | 0.82 | CHRNB2 (0.69) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130184313-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-07-18 | — | — | US | disclosed |
| US-8445684-B2 | Nicotinic acetylcholine receptor ligands and the uses thereof | PsycoGenics Inc. (US) | 2013-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184313-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF | CHRNG, CHRNA5, CHRNA2 | CHRNB2 12/4885CHRNA4 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.