Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346581 | 0.89 | MAPT (0.35) | ALDH1A1MAPTKMT2AKDM4EGAA | |
| SCHEMBL130243 | 0.85 | ALDH1A1 (0.44) | ALDH1A1CYP3A4MAPTKMT2AKDM4E | |
| SCHEMBL3709630 | 0.83 | TSHR (0.34) | ALDH1A1CYP3A4KMT2AMEN1TSHR | |
| SCHEMBL28860546 | 0.80 | CNR2 (0.39) | ALDH1A1KDM4ENPC1RAB9ATDP1 | |
| SCHEMBL27670512 | 0.79 | DRD4 (0.36) | ALDH1A1CYP3A4MAPTKMT2AGAA | |
| SCHEMBL3039791 | 0.78 | KMT2A (0.41) | ALDH1A1CYP3A4MAPTKMT2AKDM4E | |
| SCHEMBL131242 | 0.78 | CNR2 (0.31) | TSHRL3MBTL1 | |
| SCHEMBL133939 | 0.77 | TSHR (0.55) | ALDH1A1CYP3A4MAPTKMT2AKDM4E | |
| SCHEMBL27948257 | 0.77 | CNR2 (0.31) | — | |
| SCHEMBL9458404 | 0.76 | TSHR (0.34) | ALDH1A1CYP3A4TSHRNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8444716-B1 | Soluble solid hair coloring article | THE PROCTER & GAMBLE COMPANY (US) | 2013-05-21 | — | — | US | disclosed |