Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | S100B | P04271 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14949883 | 0.85 | ALDH1A1 (0.37) | ALDH1A1CYP3A4TSHRL3MBTL1PSMD14 | |
| SCHEMBL3709630 | 0.85 | TSHR (0.34) | ALDH1A1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL9458404 | 0.85 | TSHR (0.34) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL27658222 | 0.84 | TSHR (0.68) | ALDH1A1TSHRL3MBTL1MAPK1TDP1 | |
| SCHEMBL27587413 | 0.84 | TSHR (0.33) | ALDH1A1CYP3A4TSHRALDH3A1ALDH1A3 | |
| SCHEMBL131242 | 0.83 | CNR2 (0.31) | TSHRL3MBTL1CNR2 | |
| SCHEMBL28860546 | 0.82 | CNR2 (0.39) | ALDH1A1TDP1CNR2RAB9ANPC1 | |
| SCHEMBL27948257 | 0.82 | CNR2 (0.31) | CNR2 | |
| SCHEMBL27670512 | 0.81 | DRD4 (0.36) | ALDH1A1CYP3A4TSHRGFERMEN1 | |
| SCHEMBL4467275 | 0.81 | ADRA2A (0.35) | ALDH1A1CYP3A4TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217539-A1 | ANTIVIRAL COMPOUNDS AND COMPOSITIONS THEREFROM | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2023-11-16 | — | — | WO | claimed |
| EP-4276093-A1 | ANTIVIRAL COMPOUNDS AND COMPOSITIONS THEREFROM | Consejo Superior De Investigaciones Científicas (ES) | 2023-11-15 | — | — | EP | claimed |
| CN-113135922-B | Azepane [4,3,2-cd ] isoindol-2-one derivatives and application thereof | 中国药科大学 | 2023-05-30 | — | — | CN | claimed |
| CN-113135922-A | Azacycloheptane [4,3,2-cd ] isoindol-2-one derivatives and application thereof | 中国药科大学 | 2021-07-20 | — | — | CN | claimed |
| CN-111377923-A | Pyrido [3',2':6, 7] azepino [4,3,2-cd ] isoindolone derivatives and application thereof | 中国药科大学 | 2020-07-07 | — | — | CN | claimed |
| CN-107141391-B | Ethylene-polar styrene quasi-random copolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-03-13 | — | — | CN | claimed |
| US-10294246-B2 | Substituted boronic acids and boronate esters as immunoproteasome inhibitors | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | claimed |
| EP-3400231-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS | Technion Research & Development Foundation Limited (IL) | 2018-11-14 | — | — | EP | claimed |
| EP-3344641-A1 | AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS | Eloxx Pharmaceuticals Ltd. (IL) | 2018-07-11 | — | — | EP | claimed |
| EP-2803663-B1 | Human protein tyrosine phosphatase inhibitors and their pharmaceutical use | AERPIO THERAPEUTICS INC (US) | 2017-11-29 | — | — | EP | claimed |
| US-6509426-B2 | Dichloro(1,1'-dimethylsilylenebis(2-methyl-4-(4-methoxyphenyl) -4H-azulenyl))zirconium, for example; can produce polyolefin with high molecular weight and high melting point for extrusion or injection moldability | JAPAN POLYCHEM CORPORATION (JP) | 2003-01-21 | — | — | US | claimed |
| US-6455525-B1 | Heterocyclic substituted pyrazolones | CEPHALON, INC. | 2002-09-24 | — | — | US | claimed |
| EP-1226141-A1 | HETEROCYCLIC SUBSTITUTED PYRAZOLONES | CEPHALON, INC. (US) | 2002-07-31 | — | — | EP | claimed |
| EP-1124791-A1 | SURFACE FUNCTIONALISATION | ISIS INNOVATION LIMITED (GB) | 2001-08-22 | — | — | EP | claimed |
| WO-2001032653-A1 | HETEROCYCLIC SUBSTITUTED PYRAZOLONES | CEPHALON, INC. (US) | 2001-05-10 | — | — | WO | claimed |
| WO-2000026180-A1 | SURFACE FUNCTIONALISATION | ISIS INNOVATION LIMITED (GB) | 2000-05-11 | — | — | WO | claimed |
| US-5656745-A | AMIDATE LINKAGE; ANTITUMOR, ANTICARCINOGENIC AGENTS | GILEAD SCIENCES, INC. (US) | 1997-08-12 | — | — | US | claimed |
| EP-0034349-B1 | NOVEL PYRIDINECARBOXAMIDE DERIVATIVES, A PROCESS FOR THE PREPARATION THEREOF, THE USE OF SAID DERIVATIVES AND A PHARMACEUTICAL COMPOSITION CONTAINING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1983-12-14 | — | — | EP | claimed |
| EP-0000616-B1 | MATRIX ADDRESSABLE ELECTROCHROMIC DISPLAY DEVICE | International Business Machines Corporation (US) | 1981-11-25 | — | — | EP | claimed |
| EP-0034349-A2 | Novel pyridinecarboxamide derivatives, a process for the preparation thereof, the use of said derivatives and a pharmaceutical composition containing same | Tanabe Seiyaku Co., Ltd. (JP) | 1981-08-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294246-B2 | Substituted boronic acids and boronate esters as immunoproteasome inhibitors | PSMB7, PSMA7, PSMB11 | ALDH1A1 2896/4885CYP3A4 3910/4885TSHR 4102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.