Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13697492 | 0.91 | CALCRL (0.56) | CMA1CALCRLSLC6A2OPRM1OPRD1 | |
| SCHEMBL14947061 | 0.87 | CALCRL (0.47) | CMA1CALCRLOPRM1OPRD1EPHA2 | |
| SCHEMBL31275697 | 0.84 | SLC6A2 (0.59) | CMA1CALCRLSLC6A2AGTR2AGTR1 | |
| SCHEMBL29701313 | 0.84 | CALCRL (0.59) | CMA1CALCRLSLC6A2OPRM1OPRD1 | |
| SCHEMBL30973949 | 0.84 | OPRM1 (0.59) | CMA1SLC6A2OPRM1OPRD1 | |
| SCHEMBL32677399 | 0.83 | BACE1 (0.53) | CMA1CALCRLAGTR2AGTR1F2 | |
| SCHEMBL29856163 | 0.82 | SLC6A2 (0.58) | CMA1CALCRLSLC6A2OPRM1OPRD1 | |
| SCHEMBL31266639 | 0.82 | AGTR1 (0.53) | CALCRLSLC6A2AGTR2AGTR1NTSR2 | |
| SCHEMBL30494482 | 0.81 | F2 (0.57) | CALCRLSLC6A2OPRM1OPRD1EPHA2 | |
| SCHEMBL31206300 | 0.81 | EPHA2 (0.58) | CMA1CALCRLSLC6A2APLNRAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150899-B2 | Identification of compounds modifying a cellular response | 2CUREX (DK) | 2015-10-06 | — | — | US | disclosed |
| US-20130123140-A1 | IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE | 2CUREX (DK) | 2013-05-16 | — | — | US | disclosed |