Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950284 | 0.90 | FAAH (0.66) | FAAHCES2GRM5GRIN2BKMO | |
| SCHEMBL427868 | 0.90 | FAAH (0.59) | FAAHCES2TGFBR1 | |
| SCHEMBL526192 | 0.89 | FAAH (0.67) | FAAHCES2GRM5KMO | |
| SCHEMBL14950261 | 0.89 | FAAH (0.53) | FAAHCES2GRIN2BLMNATGFBR1 | |
| SCHEMBL16424253 | 0.88 | FAAH (0.53) | FAAHCES2TGFBR1 | |
| SCHEMBL427343 | 0.85 | FAAH (0.54) | FAAHCES2TGFBR1 | |
| SCHEMBL14937765 | 0.85 | FAAH (0.52) | FAAHCES2LMNA | |
| SCHEMBL14950257 | 0.84 | FAAH (0.52) | FAAHCES2GRIN2B | |
| SCHEMBL427732 | 0.84 | FAAH (0.53) | FAAHCES2TGFBR1MCHR1 | |
| SCHEMBL426220 | 0.84 | FAAH (0.53) | FAAHCES2TGFBR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123493-A1 | PROCESS FOR THE SYNTHESIS OF SUBSTITUTED UREA COMPOUNDS | BIAL - PORTELA & CA, S.A. (PT) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123493-A1 | PROCESS FOR THE SYNTHESIS OF SUBSTITUTED UREA COMPOUNDS | UTS2R, ARG1, PRMT1 | FAAH 2166/4885CES2 463/4885GRM5 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.