Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 8/20 | 0.45 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13843585 | 0.82 | TRPA1 (0.47) | TRPA1GSRLMNABLMMEN1 | |
| SCHEMBL14945485 | 0.82 | TRPA1 (0.47) | TRPA1GSRLMNABLMMEN1 | |
| SCHEMBL14935978 | 0.80 | GSR (0.50) | TRPA1GSRLMNABLMTAAR1 | |
| SCHEMBL14935912 | 0.80 | GSR (0.50) | TRPA1GSRLMNABLMTAAR1 | |
| SCHEMBL16398170 | 0.80 | GSR (0.50) | TRPA1GSRLMNABLMTAAR1 | |
| SCHEMBL4426985 | 0.79 | GSR (0.57) | TRPA1GSRLMNABLMTAAR1 | |
| SCHEMBL8602813 | 0.78 | GSR (0.49) | TRPA1GSRLMNABLMTAAR1 | |
| SCHEMBL22891053 | 0.76 | GSR (0.44) | TRPA1GSRLMNABLMGPR88 | |
| SCHEMBL7417686 | 0.74 | GSR (0.49) | TRPA1GSRLMNABLMKMT2A | |
| SCHEMBL5902915 | 0.74 | GSR (0.52) | TRPA1GSRLMNABLMTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013071169-A1 | ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. (US) | 2013-05-16 | — | — | WO | disclosed |