Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12812945 | 0.89 | HCAR1 (0.38) | HCAR1KDM4ENPSR1FSCN1TNF | |
| SCHEMBL1233768 | 0.85 | HCAR1 (0.40) | HCAR1KDM4ENPSR1FSCN1TNF | |
| SCHEMBL29558810 | 0.85 | HCAR1 (0.40) | HCAR1KDM4ENPSR1FSCN1TNF | |
| SCHEMBL12812941 | 0.82 | HCAR1 (0.37) | HCAR1KDM4ENPSR1FSCN1TNF | |
| SCHEMBL27834793 | 0.81 | HCAR1 (0.38) | HCAR1KDM4ENPSR1FSCN1ALDH1A1 | |
| SCHEMBL12880385 | 0.78 | — | — | |
| SCHEMBL12880398 | 0.76 | — | — | |
| SCHEMBL2913915 | 0.74 | POLB (0.38) | HCAR1FSCN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL2922803 | 0.72 | FFAR4 (0.33) | HCAR1 | |
| SCHEMBL1200187 | 0.71 | KDM4E (0.37) | HCAR1KDM4ENPSR1FSCN1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467021-B1 | 3-[1-(3-HALOALKYL)-TRIAZOLYL]-PHENYL-SULPHIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER IP GMBH (DE) | 2015-10-28 | — | — | EP | disclosed |
| US-8632767-B2 | 3-[1-(3-haloalkyl)triazolyl]phenyl sulphide derivatives as acaricides and insecticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| US-8632767-B2 | 3-[1-(3-haloalkyl)triazolyl]phenyl sulphide derivatives as acaricides and insecticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| US-20110077410-A1 | Process for the Preparation of 1-Phenyl-1,2,4-triazoles | BAYER CROPSCIENCE AG (DE) | 2011-03-31 | — | — | US | disclosed |
| US-20110045104-A1 | 3-[1-(3-Haloalkyl)triazolyl]phenyl sulphide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG (DE) | 2011-02-24 | — | — | US | disclosed |
| US-20110045104-A1 | 3-[1-(3-Haloalkyl)triazolyl]phenyl sulphide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG (DE) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110045104-A1 | 3-[1-(3-Haloalkyl)triazolyl]phenyl sulphide derivatives as acaricides and insecticides | ATL3, PDIA3, NAT1 | HCAR1 3197/4885KDM4E 4319/4885NPSR1 1097/4885 |
| US-20110077410-A1 | Process for the Preparation of 1-Phenyl-1,2,4-triazoles | CYP4B1, PAH, CYP3A4 | HCAR1 2743/4885KDM4E 941/4885NPSR1 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.