SCHEMBL1495372

SCHEMBL1495372

O=[PH](c1ccccc1)c1ccccc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DBH P09172 2/20 0.41
MMP2 P08253 1/20 0.41
CA2 P00918 5/20 0.39
ALDH1A1 P00352 5/20 0.39
HPGD P15428 4/20 0.39
CA12 O43570 4/20 0.39
CA14 Q9ULX7 4/20 0.39
CA4 P22748 4/20 0.39
KDM4E B2RXH2 3/20 0.39
HSD17B10 Q99714 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP3A4 P08684 2/20 0.39
NFKB1 P19838 2/20 0.39
MAPT P10636 2/20 0.39
ALOX15 P16050 2/20 0.39
CA3 P07451 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
NPC1 O15118 1/20 0.39
GMNN O75496 1/20 0.39
EGFR P00533 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL28189076 0.90 CA12 (0.41) DBHMMP2CA2ALDH1A1HPGD
SCHEMBL1496292 0.85 ALDH1A1 (0.47) DBHMMP2CA2ALDH1A1HPGD
SCHEMBL821937 0.83 ALDH1A1 (0.30) ALDH1A1
SCHEMBL5827166 0.79 GAA (0.41) CA2ALDH1A1CA12CA14CYP3A4
SCHEMBL5605347 0.75 ALDH1A1 (0.57) CA2ALDH1A1HPGDCA12CA14
SCHEMBL1667 0.74 ALDH1A1 (0.35) CA2ALDH1A1CA12CA14CA4
SCHEMBL13583073 0.74 ALDH1A1 (0.35) CA2ALDH1A1CA12CA14CA4
SCHEMBL27297316 0.73 ALDH1A1 (0.45) DBHMMP2CA2ALDH1A1HPGD
Phenol SCHEMBL28034626 0.73 CA12 (0.58) DBHMMP2CA2ALDH1A1HPGD
SCHEMBL2154560 0.73 TSHR (0.39) ALDH1A1HPGDKDM4EHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104987664-A Insulation-layer mold-pressed structural member for extra-high-voltage direct-current power transmission and transformation and preparation method thereof SICHUAN DONGFANG INSULATING MATERIAL CO LTD 2015-10-21 CN claimed
CN-102433001-A Halogen-free flame-retardant material composition and application thereof in bonding sheet, copper-clad plate and laminated plate HUASHUO TECHNOLOGY CO LTD 2012-05-02 CN claimed
CN-1224635-C High refractive index thermoplastic polyphosphonates JOHNSON & JOHNSON VISION CARE (US) 2005-10-26 CN claimed
CN-1147740-C Melt polymer synthesis of poly ether phosphine oxides �ǿƷ ��ޱ���˹�� 2004-04-28 CN claimed
CN-1423678-A Flame retardant phosphorus element-containing epoxy resin compositions DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-11 CN claimed
CN-1387545-A High refractive index thermoplastic polyphosphonates JOHNSON & JOHNSON VISION CARE (US) 2002-12-25 CN claimed
CN-1338056-A Melt polymer synthesis of poly ether phosphine oxides JOHNSON & JOHNSON VISION PROD (US) 2002-02-27 CN claimed
EP-2475716-B1 HYDROXYPHENYL PHOSPHINE OXIDE MIXTURES AND THEIR USE AS FLAME RETARDANTS FOR EPOXY RESINS CHEMTURA CORP (US) 2017-04-19 EP disclosed
CN-103347924-B High performance thermoset materials for electrical laminate, high density interconnect, and interconnect substrate applications 蓝立方知识产权有限责任公司 2016-12-28 CN disclosed
CN-106165175-A High molecular electrolyte composition and use its polyelectrolyte membrane, film electrode composite element and polymer electrolyte fuel cell 东丽株式会社 2016-11-23 CN disclosed
US-9388340-B2 Preparation of hydroxyphenyl phosphine oxide mixtures CHEMTURA CORPORATION (US) 2016-07-12 US disclosed
CN-105705548-A Curable compositions which form interpenetrating polymer networks 蓝立方知识产权有限责任公司 2016-06-22 CN disclosed
US-20160168469-A9 Preparation of Hydroxyphenyl Phosphine Oxide Mixtures LANXESS SOLUTIONS US INC. 2016-06-16 US disclosed
CN-1423678-A Flame retardant phosphorus element-containing epoxy resin compositions DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-11 CN disclosed
CN-1387545-A High refractive index thermoplastic polyphosphonates JOHNSON & JOHNSON VISION CARE (US) 2002-12-25 CN disclosed
CN-1338056-A Melt polymer synthesis of poly ether phosphine oxides JOHNSON & JOHNSON VISION PROD (US) 2002-02-27 CN disclosed
EP-0183290-B1 A PROCESS FOR THE PREPARATION OF BIS-PHOSPHINEOXIDE COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-05-24 EP disclosed
US-4720589-A Bis-phosphineoxide compounds SHELL OIL COMPANY (US) 1988-01-19 US disclosed
US-4683338-A Process for the preparation of bis-phosphineoxide compounds SHELL OIL COMPANY (US) 1987-07-28 US disclosed
EP-0183290-A1 A process for the preparation of bis-phosphineoxide compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-06-04 EP disclosed