Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1495372 | 0.79 | DBH (0.41) | GAAPOLBCA12CA1CA2 | |
| Phenol SCHEMBL28189076 | 0.76 | CA12 (0.41) | POLBCA12CA1CA2CA7 | |
| SCHEMBL27472420 | 0.74 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| Phenol SCHEMBL28034626 | 0.72 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29779662 | 0.72 | ALOX5 (0.44) | ALOX5CA12CA9ALDH1A1HSP90AA1 | |
| SCHEMBL821937 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL28729948 | 0.69 | MMP3 (0.58) | ALOX5CA12CA1CA2CA9 | |
| SCHEMBL13583073 | 0.68 | ALDH1A1 (0.35) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1667 | 0.68 | ALDH1A1 (0.35) | CA12CA1CA2CA7CA9 | |
| Methyl Alcohol SCHEMBL28358130 | 0.67 | CA2 (0.38) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109287-B2 | Space environmentally durable polyimides and copolyimides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2006-09-19 | — | — | US | disclosed |
| US-20050137383-A1 | Space environmentally durable polyimides and copolyimides | U. S. A. AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2005-06-23 | — | — | US | disclosed |
| US-6841652-B2 | Space environmentally durable polyimides and copolyimides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2005-01-11 | — | — | US | disclosed |
| US-20030045670-A1 | Space environmentally durable polyimides and copolyimides | NATIONAL AERONAUTICS AND SPACE ADMINISTRATION | 2003-03-06 | — | — | US | disclosed |
| WO-2002092654-A2 | SPACE ENVIRONMENTALLY DURABLE POLYIMIDES AND COPOLYIMIDES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (NASA) (US) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045670-A1 | Space environmentally durable polyimides and copolyimides | MAGI3, PADI4, PADI3 | GAA 3790/4885POLB 2072/4885GFER 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.