Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Choline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Choline SCHEMBL30612764 | 1.00 | — | — | |
| Choline SCHEMBL1332010 | 1.00 | — | — | |
| Choline SCHEMBL2459999 | 1.00 | CYP3A4 (1.00) | — | |
| Choline SCHEMBL28574484 | 1.00 | CYP3A4 (1.00) | — | |
| Choline SCHEMBL1330530 | 1.00 | — | — | |
| Choline SCHEMBL9391204 | 1.00 | CYP3A4 (1.00) | — | |
| Choline SCHEMBL29499824 | 1.00 | — | — | |
| Choline SCHEMBL2935374 | 0.96 | CYP3A4 (0.93) | — | |
| Choline SCHEMBL8516093 | 0.96 | CYP3A4 (0.93) | — | |
| Choline SCHEMBL4947815 | 0.96 | CYP3A4 (0.93) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 72628 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204609-B1 | COMPOSITIONS AND METHODS FOR THE ELECTRODEPOSITION OF NANOTWINNED COPPER | MACDERMID ENTHONE INC (US) | 2026-05-27 | — | — | EP | claimed |
| EP-4401580-B1 | SOLID COMPOSITION SUITABLE AS A NUTRITIONAL COMPOSITION OR SUPPLEMENT FOR ANIMALS THAT SUFFER FROM BRAIN RELATED DISORDERS, DECLINE OR DISEASES | NUTRICIA NV (NL) | 2026-05-27 | — | — | EP | claimed |
| EP-4748443-A2 | SOLID COMPOSITION SUITABLE AS A NUTRITIONAL COMPOSITION OR SUPPLEMENT FOR ANIMALS THAT SUFFER FROM BRAIN RELATED DISORDERS, DECLINE OR DISEASES | N.V. Nutricia (NL) | 2026-05-27 | — | — | EP | claimed |
| CN-122081001-A | Vegetable oil extraction method | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080253-A | Preparation method of nano chitin by eutectic solvent one-pot method | — | 2026-05-26 | — | — | CN | claimed |
| CN-122094573-A | Sweetener composition and method for preparing the same | — | 2026-05-26 | — | — | CN | claimed |
| CN-118318936-B | Functional feed for improving quality of cabin-cultured large yellow croaker | OCEAN UNIVERSITY OF CHINA (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-115052702-B | Electrolyte solution | Tex Shejet LLC (GB) | 2026-05-26 | — | — | CN | claimed |
| CN-121379932-B | Culture medium for high-density serum-free suspension culture of BHK-21 cells and application thereof | Zhongsheng tianxinhe (Wuxi) Biotechnology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122084727-A | Method for detecting and separating eight flavonoid glycoside compounds with similar structures by utilizing capillary zone electrophoresis | — | 2026-05-26 | — | — | CN | claimed |
| US-4167562-A | Method and composition for treating arteriosclerosis | EVERS H RAY | 1979-09-11 | — | — | US | claimed |
| EP-0002857-A1 | Laundry detergent substrate articles | THE PROCTER & GAMBLE COMPANY (US) | 1979-07-11 | — | — | EP | claimed |
| EP-0002315-A1 | Apparatus and method for producing coated film | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-06-13 | — | — | EP | claimed |
| EP-0001924-A1 | Pharmaceutical composition for administering choline | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1979-05-16 | — | — | EP | claimed |
| US-4117013-A | AMINES, QUATERNARY AMMONIUM COMPOUNDS, OLEFIN EPOXIDES, HYDROXYQUI(OLINES, AMINE PHENOXIDES, GLYCIDYL HALIDES AND ETHERS | UNITED TECHNOLOGIES CORPORATION (US) | 1978-09-26 | — | — | US | claimed |
| US-4042733-A | Forming solid, adhesive-free composite of membrane filters and cellulosic cardboard | BOEHRINGER INGELHEIM GMBH (DT) | 1977-08-16 | — | — | US | claimed |
| US-4021447-A | SILICA, ALUMINA, ALKALI METAL, WATER, CHOLINE AND PYRROLIDINE | MOBIL OIL CORPORATION (US) | 1977-05-03 | — | — | US | claimed |
| US-3957869-A | N-(CHLOROALKOXYMETHYL)ACRYLAMIDES, QUATERNARY AMMONIUM DERIVATIVES THEREOF, AND POLYMERS HAVING A CONTENT THEREOF | AMERICAN CYANAMID COMPANY (US) | 1976-05-18 | — | — | US | claimed |
| US-3950546-A | ALUMINUM SILICATE, SODIUM BENTONITE | MUSIC CITY SUPPLEMENT COMPANY (US) | 1976-04-13 | — | — | US | claimed |
| US-3943122-A | Polyazo compounds containing benzhydrol as a component | PECHINEY UGINE KUHLMANN (FR) | 1976-03-09 | — | — | US | claimed |