Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Choline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.86 |
| ▸ | LMNA | P02545 | 3/20 | 0.86 |
| ▸ | APEX1 | P27695 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Choline SCHEMBL30612764 | 1.00 | — | — | |
| Choline SCHEMBL1332010 | 1.00 | — | — | |
| Choline SCHEMBL28574484 | 1.00 | CYP3A4 (1.00) | CYP3A4SLC5A7MEN1KMT2ALMNA | |
| Choline SCHEMBL1330530 | 1.00 | — | — | |
| Choline SCHEMBL9391204 | 1.00 | CYP3A4 (1.00) | CYP3A4SLC5A7MEN1KMT2ALMNA | |
| Choline SCHEMBL14957 | 1.00 | — | — | |
| Choline SCHEMBL29499824 | 1.00 | — | — | |
| Choline SCHEMBL2935374 | 0.96 | CYP3A4 (0.93) | CYP3A4SLC5A7MEN1KMT2ALMNA | |
| Choline SCHEMBL8516093 | 0.96 | CYP3A4 (0.93) | CYP3A4SLC5A7MEN1KMT2ALMNA | |
| Choline SCHEMBL4947815 | 0.96 | CYP3A4 (0.93) | CYP3A4SLC5A7MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 571 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117039207-B | Battery, iodine electrode material and preparation method of electrolyte | 广东工业大学 | 2024-07-30 | — | — | CN | claimed |
| CN-117039207-A | Battery, iodine electrode material and preparation method of electrolyte | 广东工业大学 | 2023-11-10 | — | — | CN | claimed |
| CN-116178316-A | Method for preparing 5-hydroxymethyl-2-furaldehyde by using fructose | 中国科学院宁波材料技术与工程研究所 | 2023-05-30 | — | — | CN | claimed |
| WO-2023072053-A1 | METHOD AND SYSTEM FOR CONTINUOUSLY PRODUCING 5-HYDROXYMETHYLFURFURAL AND 2,5-FURANDICARBOXYLIC ACID | 中国石油化工股份有限公司 | 2023-05-04 | — | — | WO | claimed |
| CN-109701619-B | Molecular sieve with SSZ-13/SSZ-39 composite structure and synthesis method thereof | 中国石油化工股份有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-107777699-B | ZSM-11/SSZ-13 composite structure molecular sieve and synthetic method thereof | 中国石油化工股份有限公司 | 2020-11-03 | — | — | CN | claimed |
| CN-105660702-A | Herbaceous plant growth regulator | 天津佳瑞兴科技发展有限公司 | 2016-06-15 | — | — | CN | claimed |
| CN-105660079-A | New method for preventing malformed fruits of space green peppers | 璧典附 | 2016-06-15 | — | — | CN | claimed |
| CN-105660111-A | High-yield cultivating method for corn in dry-farming area of northern cold region | 中国科学院东北地理与农业生态研究所 | 2016-06-15 | — | — | CN | claimed |
| CN-105669316-A | Special organic fertilizer for Gentiana macrophylla and preparation method thereof | 刘发元 | 2016-06-15 | — | — | CN | claimed |
| CN-1699302-A | Fertilizer with release-controlled function for strengthening root and inhibiting growth | SICHUAN LIZI ECO TECH CO LTD (CN) | 2005-11-23 | — | — | CN | claimed |
| CN-1556076-A | Growth regulating type paddy rice special long effact fertilizer | 广东省农业科学院土壤肥料研究所 | 2004-12-22 | — | — | CN | claimed |
| CN-1357520-A | Regularly released granular organic fertilizer and its production process | CHU SHIWEI CN | 2002-07-10 | — | — | CN | claimed |
| CN-1346818-A | Process for preparing magnetized multi-element biological-bacterial fertilizer | LI SHAOYONG (CN) | 2002-05-01 | — | — | CN | claimed |
| CN-1238323-A | Leaf fertilizer | YIN XIAOZHE (CN) | 1999-12-15 | — | — | CN | claimed |
| CN-1172094-A | Multifunctional vegetable seedlings nutritious mother agent and its preparation method | SHENYANG INST OF APPLED ECOLOG (CN) | 1998-02-04 | — | — | CN | claimed |
| CN-1154352-A | Plant leaves fertilizer | SIDAER CHEMICAL NEW TECH CORP (CN) | 1997-07-16 | — | — | CN | claimed |
| CN-1123266-A | Liquid plant-foliage fertilizer and preparation method thereof | ZHANG KEXU (CN) | 1996-05-29 | — | — | CN | claimed |
| CN-1095107-A | Seaweed beta-carotene production-agent increasing | INST OCEANOLOGY CHINESE ACAD (CN) | 1994-11-16 | — | — | CN | claimed |
| CN-1054966-A | Composite for crop root external nutrient spray fertilizer and production process thereof | GUIPING POTASSIUM DIHYDROGEN P (CN) | 1991-10-02 | — | — | CN | claimed |