Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14769305 | 0.83 | GBA1 (0.39) | GBA1 | |
| SCHEMBL18349328 | 0.82 | GBA1 (0.38) | GBA1 | |
| SCHEMBL16187681 | 0.82 | GBA1 (0.38) | GBA1 | |
| SCHEMBL18842858 | 0.80 | TK1 (0.34) | GBA1 | |
| SCHEMBL14477759 | 0.80 | OGA (0.35) | GBA1 | |
| SCHEMBL15756359 | 0.78 | CYP2D6 (0.35) | — | |
| SCHEMBL18220481 | 0.78 | CYP2D6 (0.35) | — | |
| SCHEMBL26285165 | 0.76 | SSTR1 (0.32) | — | |
| SCHEMBL14477755 | 0.75 | GBA1 (0.33) | GBA1 | |
| SCHEMBL14958608 | 0.75 | GBA1 (0.33) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045512-B2 | 6″-amino-6″-deoxygalactosylceramides | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-06-02 | — | — | US | disclosed |
| US-20140037693-A1 | 6\"-AMINO-6\"-DEOXYGALACTOSYLCERAMIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-02-06 | — | — | US | disclosed |
| US-8445272-B2 | Method of stimulating NKT with 6″-amino-6″-deoxygalactosylceramides | THE SCRIPPS RESEARCH INSTITUTE (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120028915-A1 | 6\"-AMINO-6\"-DEOXYGALACTOSYLCERAMIDES | THE SCRIPPS RESEACH INSTITUTE (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028915-A1 | 6\"-AMINO-6\"-DEOXYGALACTOSYLCERAMIDES | FUT6, GALNT6, ST6GAL1 | GBA1 7/4885 |
| US-20140037693-A1 | 6\"-AMINO-6\"-DEOXYGALACTOSYLCERAMIDES | FUT6, GALNT6, ST6GAL1 | GBA1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.