Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440273 | 0.89 | LMNA (0.52) | LMNAKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL3444298 | 0.83 | LMNA (0.53) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL3444079 | 0.82 | LMNA (0.60) | LMNAKMT2AMEN1SMN1; SMN2BDKRB1 | |
| SCHEMBL3440398 | 0.81 | LMNA (0.56) | LMNAKMT2AMEN1SMN1; SMN2BDKRB1 | |
| SCHEMBL3443833 | 0.81 | LMNA (0.50) | LMNAKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL10118754 | 0.80 | LMNA (0.49) | LMNAKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL3443843 | 0.78 | LMNA (0.48) | LMNAKMT2AALDH1A1MEN1RAB9A | |
| SCHEMBL14958754 | 0.77 | MAPT (0.54) | LMNAKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL3440493 | 0.77 | LMNA (0.47) | LMNAKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL10118935 | 0.77 | LMNA (0.46) | LMNAKMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-B1 | Analgetic phenylsulphonamides | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |