Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.37 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440010 | 0.84 | BDKRB1 (0.50) | LMNABDKRB1 | |
| SCHEMBL15372732 | 0.81 | PKM (0.39) | FABP4PKMKEAP1NFE2L2GLA | |
| SCHEMBL3440723 | 0.78 | MCL1 (0.45) | LMNABDKRB1 | |
| SCHEMBL3440038 | 0.77 | AVPR1B (0.45) | LMNABDKRB1ALDH1A1 | |
| SCHEMBL12046776 | 0.76 | ALDH1A1 (0.41) | GAAPKMGLAMAPTLMNA | |
| SCHEMBL4894187 | 0.76 | PKM (0.49) | FABP4PKMKEAP1NFE2L2GLA | |
| SCHEMBL3007624 | 0.76 | BDKRB1 (0.49) | GAALMNABDKRB1 | |
| SCHEMBL13942842 | 0.75 | BDKRB1 (0.48) | BDKRB1 | |
| SCHEMBL3440369 | 0.75 | BDKRB1 (0.48) | GAABDKRB1 | |
| SCHEMBL14033588 | 0.73 | BDKRB1 (0.56) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284166-B1 | Arylsulfonamides with analgetic activity | BOEHRINGER INGELHEIM INT (DE) | 2013-10-16 | — | — | EP | disclosed |
| EP-2402329-B1 | Analgetic phenylsulphonamides | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |