Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455878 | 0.80 | EPHX2 (0.42) | EPHX2NR1H4HDAC1HMGCRALDH1A1 | |
| SCHEMBL440134 | 0.71 | ALDH1A1 (0.44) | HDAC1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL2029488 | 0.69 | HDAC1 (0.43) | HDAC1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL13981576 | 0.67 | NPY5R (0.42) | HDAC1MAPT | |
| SCHEMBL13321994 | 0.67 | ALDH1A1 (0.41) | HDAC1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL13321993 | 0.67 | ALDH1A1 (0.41) | HDAC1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL12709305 | 0.66 | KMT2A (0.41) | HDAC1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10310970 | 0.66 | HDAC1 (0.38) | HDAC1ALDH1A1SMN1; SMN2NR1I2 | |
| SCHEMBL18392890 | 0.66 | MEN1 (0.38) | HDAC1ALDH1A1MAPTSMN1; SMN2NR1I2 | |
| SCHEMBL14298987 | 0.66 | HDAC1 (0.35) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445695-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-05-21 | — | — | US | disclosed |