Sugi Predict

Sugi Predict / Compounds / SCHEMBL440134

SCHEMBL440134

SCHEMBL440134

CCOP(=O)(Cc1ccc(C=O)cc1)OCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.44
▸ LMNA P02545 2/20 0.44
▸ MAPT P10636 2/20 0.44
▸ HPGD P15428 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ NPY5R Q15761 1/20 0.40
▸ ALDH1A3 P47895 2/20 0.40
▸ ALDH3A1 P30838 1/20 0.40
▸ TSHR P16473 1/20 0.39
▸ CYP2A6 P11509 2/20 0.38
▸ TLR8 Q9NR97 1/20 0.38
▸ TLR7 Q9NYK1 1/20 0.38
▸ KMT2A Q03164 1/20 0.37
▸ CCNT1 O60563 2/20 0.37
▸ CDK9 P50750 2/20 0.37
▸ NR1I2 O75469 1/20 0.37
▸ TACR2 P21452 1/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ POLB P06746 1/20 0.35
▸ AOX1 Q06278 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13321993 0.95 ALDH1A1 (0.41) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
SCHEMBL13321994 0.95 ALDH1A1 (0.41) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
SCHEMBL455878 0.91 EPHX2 (0.42) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
SCHEMBL13451262 0.87 NPY5R (0.41) ALDH1A1MAPTHPGDNPY5RTSHR
SCHEMBL3375825 0.87 TSHR (0.50) MAPTNPY5RTSHRTLR8TLR7
SCHEMBL13321999 0.86 KDM4E (0.40) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
SCHEMBL5537640 0.84 NPY5R (0.42) ALDH1A1MAPTNPY5RTSHRTLR8
SCHEMBL14437823 0.81 RELA (0.41) ALDH1A1LMNAMAPTHPGDNPY5R
SCHEMBL2493713 0.81 TSHR (0.44) MAPTNPY5RTSHRTLR8TLR7
SCHEMBL16062693 0.81 POLB (0.46) ALDH1A1MAPTSMN1; SMN2NPY5RTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240270762-A1 PENICILLIN-BINDING PROTEIN INHIBITORS SPRING MILL PHARMA, INC. 2024-08-15 — — US disclosed
EP-3269745-B1 FUNCTIONALIZED ELASTOMER VIA ALLYLBORATION GOODYEAR TIRE & RUBBER (US) 2019-04-03 — — EP disclosed
EP-3269745-A1 FUNCTIONALIZED ELASTOMER VIA ALLYLBORATION The Goodyear Tire & Rubber Company (US) 2018-01-17 — — EP disclosed
US-9580532-B1 Functionalized elastomer via allylboration THE GOODYEAR TIRE & RUBBER COMPANY (US) 2017-02-28 — — US disclosed
US-9580532-B1 Functionalized elastomer via allylboration THE GOODYEAR TIRE & RUBBER COMPANY (US) 2017-02-28 — — US disclosed
US-9574024-B1 Method of making a functionalized elastomer via allylboration THE GOODYEAR TIRE & RUBBER COMPANY (US) 2017-02-21 — — US disclosed
US-9574024-B1 Method of making a functionalized elastomer via allylboration THE GOODYEAR TIRE & RUBBER COMPANY (US) 2017-02-21 — — US disclosed
US-8445695-B2 Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces NORTH CAROLINA STATE UNIVERSITY (US) 2013-05-21 — — US disclosed
US-8445695-B2 Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces NORTH CAROLINA STATE UNIVERSITY (US) 2013-05-21 — — US disclosed
US-8445695-B2 Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces NORTH CAROLINA STATE UNIVERSITY (US) 2013-05-21 — — US disclosed
US-7314941-B2 Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces NORTH CAROLINA STATE UNIVERSITY (US) 2008-01-01 — — US disclosed
US-7314941-B2 Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces NORTH CAROLINA STATE UNIVERSITY (US) 2008-01-01 — — US disclosed
US-20070055060-A1 Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces LINDSEY JONATHAN S 2007-03-08 — — US disclosed
US-20070055060-A1 Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces LINDSEY JONATHAN S 2007-03-08 — — US disclosed
US-20070055060-A1 Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces LINDSEY JONATHAN S 2007-03-08 — — US disclosed
US-7148361-B2 For the production of solar cells and molecular memory devices NORTH CAROLINA STATE UNIVERSITY (US) 2006-12-12 — — US disclosed
US-20050096465-A1 Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces ZETTACORE, INC. 2005-05-05 — — US disclosed
EP-0313002-B1 Phenyl glycines for use in reducing neurotoxic injury SEARLE & CO (US) 1993-12-01 — — EP disclosed
US-4918064-A TREATMENT OF ANOXIA OR ISCHEMIA G. D. SEARLE & CO. (US) 1990-04-17 — — US disclosed
EP-0313002-A2 Phenyl glycines for use in reducing neurotoxic injury G.D. Searle & Co. (US) 1989-04-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050096465-A1 Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces PPOX, DAO, DDO ALDH1A1 1570/4885LMNA 4355/4885MAPT 1852/4885
US-20240270762-A1 PENICILLIN-BINDING PROTEIN INHIBITORS PEPD, BPGM, EBPL ALDH1A1 2794/4885LMNA 3468/4885MAPT 3146/4885
US-20070055060-A1 Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces PPOX, DAO, DDO ALDH1A1 1570/4885LMNA 4355/4885MAPT 1852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.