SCHEMBL1495886

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5552600	0.97	NPSR1 (0.51)	ALDH1A1HPGDHSD17B10KDM4EPOLB
	SCHEMBL1495964	0.92	NPSR1 (0.56)	ALDH1A1HPGDHSD17B10KDM4EPOLB
	Trifluoroacetic Acid SCHEMBL5549156	0.86	NOTUM (0.51)	ALDH1A1HPGDHSD17B10KDM4EPOLB
	SCHEMBL23189266	0.84	MGLL (0.46)	ALDH1A1HPGDKDM4EMEN1KMT2A
	SCHEMBL16010982	0.83	CYP4A11 (0.53)	ALDH1A1HPGDMEN1KMT2ACA1
	SCHEMBL13553385	0.83	PPARG (0.51)	ALDH1A1HPGDHSD17B10KDM4EMEN1
	SCHEMBL1495934	0.83	NR1H4 (0.51)	ALDH1A1HPGDHSD17B10KDM4EPOLB
	SCHEMBL879841	0.81	CA12 (0.46)	ALDH1A1HPGDHSD17B10KDM4EMEN1
	SCHEMBL28761815	0.81	MAPT (0.48)	ALDH1A1HPGDHSD17B10KDM4EMEN1
	SCHEMBL25721981	0.80	TDP1 (0.52)	ALDH1A1HPGDHSD17B10KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.