Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27806590 | 0.87 | MAPT (0.38) | MAPTGAALMNACA12CA1 | |
| SCHEMBL6618854 | 0.87 | ALDH1A1 (0.49) | MAPTGAALMNACA12CA1 | |
| SCHEMBL9479617 | 0.87 | CA1 (0.49) | MAPTGAALMNACA12CA1 | |
| SCHEMBL13553385 | 0.85 | PPARG (0.51) | MAPTGAALMNACA12CA1 | |
| SCHEMBL27594634 | 0.84 | NOTUM (0.53) | MAPTGAALMNACA12CA1 | |
| SCHEMBL6617704 | 0.84 | MAPT (0.46) | MAPTGAALMNACA12CA1 | |
| SCHEMBL4760486 | 0.84 | KDM4E (0.50) | MAPTGAALMNACA12CA1 | |
| SCHEMBL879841 | 0.84 | CA12 (0.46) | MAPTGAALMNACA12CA1 | |
| SCHEMBL25721981 | 0.83 | TDP1 (0.52) | MAPTGAALMNACA12CA1 | |
| SCHEMBL14175211 | 0.83 | TDP1 (0.52) | MAPTGAALMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922151-A | Substituted azole derivatives, compositions, and methods of use | TRANSTECH PHARMA INC (US) | 2007-02-28 | — | — | CN | disclosed |