SCHEMBL1495901

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Trifluoroacetic Acid SCHEMBL5552619	0.92	EPHX2 (0.43)	EPHX2MEN1KMT2ARARBHPGD
	SCHEMBL3919054	0.90	EPHX2 (0.48)	EPHX2MEN1KMT2AMAPTALDH1A1
	SCHEMBL11423248	0.86	EPHX2 (0.51)	EPHX2MEN1KMT2ARARBALDH1A1
	SCHEMBL18944340	0.86	CYP4F2 (0.41)	MEN1KMT2AHPGDMAPTALDH1A1
	SCHEMBL11290737	0.84	F13A1 (0.53)	EPHX2RARBMAPTHSD17B10LTB4R
	SCHEMBL11424107	0.83	EPHX2 (0.51)	EPHX2MEN1KMT2ARARBALDH1A1
	SCHEMBL1495869	0.83	ALDH1A1 (0.41)	EPHX2MEN1KMT2AHPGDMAPT
	SCHEMBL27341098	0.80	EPHX2 (0.50)	EPHX2MEN1KMT2AHPGDALDH1A1
	SCHEMBL5552622	0.80	ALDH1A1 (0.39)	MEN1KMT2AHPGDMAPTALDH1A1
	SCHEMBL18944342	0.79	HPGD (0.40)	MEN1KMT2AHPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.