Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1495901 | 0.79 | EPHX2 (0.45) | HPGDMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL18944340 | 0.77 | CYP4F2 (0.41) | HPGDMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL13948679 | 0.76 | CYP4F2 (0.55) | HPGDCYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL8935206 | 0.74 | CYP4F2 (0.49) | HPGDMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1495869 | 0.74 | ALDH1A1 (0.41) | HPGDMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL19000269 | 0.74 | NPSR1 (0.43) | HPGDCYP4F2CYP4A11TSHRALDH1A1 | |
| SCHEMBL18944332 | 0.73 | NPSR1 (0.44) | HPGDMEN1KMT2ATSHRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5552619 | 0.73 | EPHX2 (0.43) | HPGDMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL4131832 | 0.72 | HPGD (0.46) | HPGDMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL3247077 | 0.72 | ESR1 (0.35) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | disclosed |