Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | KIT | P10721 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 3/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14953218 | 0.82 | CA1 (0.32) | CA1CA9ACVRL1CA2CA4 | |
| SCHEMBL14953219 | 0.82 | CA1 (0.32) | CA1CA9ACVRL1CA2CA4 | |
| SCHEMBL16218840 | 0.82 | CA1 (0.32) | CA1CA9ACVRL1CA2CA4 | |
| SCHEMBL14968959 | 0.82 | CA1 (0.32) | CA1CA9ACVRL1CA2CA4 | |
| Stagonolide F SCHEMBL16940586 | 0.79 | CA1 (0.44) | CA1CA9MKNK2KDRKIT | |
| Stagonolide F SCHEMBL15516703 | 0.79 | CA1 (0.44) | CA1CA9MKNK2KDRKIT | |
| SCHEMBL16221806 | 0.79 | — | — | |
| SCHEMBL16944339 | 0.76 | CA1 (0.47) | CA1CA9MKNK2KDRKIT | |
| SCHEMBL7468957 | 0.73 | MKNK2 (0.45) | CA1CA9MKNK2KDRKIT | |
| SCHEMBL22734491 | 0.73 | MKNK2 (0.45) | CA1CA9MKNK2KDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2594561-A1 | Structural variants of mycolactones for use in modulating inflammation, immunity and pain | INSTITUT PASTEUR (FR) | 2013-05-22 | — | — | EP | disclosed |