SCHEMBL14959243

C=C1[C@H](OS)C/C(=C/C=C2\CCC[C@]3(C)[C@@H]([C@@H](C)/C=C/CC(C)(C)O[Si](C)(C)C(C)(C)C)CC[C@@H]23)C[C@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	VDR	P11473	9/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12712520	0.92	VDR (0.47)	VDR
SCHEMBL10020276	0.85	VDR (0.52)	VDR
SCHEMBL13297559	0.85	VDR (0.52)	VDR
SCHEMBL13525348	0.85	VDR (0.52)	VDR
SCHEMBL10019067	0.85	VDR (0.52)	VDR
SCHEMBL12749793	0.82	VDR (0.49)	VDR
SCHEMBL19670744	0.82	VDR (0.49)	VDR
SCHEMBL14494383	0.82	VDR (0.49)	VDR
SCHEMBL13759532	0.82	VDR (0.49)	VDR
SCHEMBL14523030	0.82	VDR (0.52)	VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8445468-B2	(20S,22E)-2-methylene-19-nor-22-ene-1α,25-dihydroxyvitamin D3	WISCONSIN ALUMNI RESEARCH FOUNDATION (US)	2013-05-21	—	—	US	disclosed