SCHEMBL14959448

SCHEMBL14959448

C/N=c1\ccc2c(-c3ccccc3C(=O)O)c3ccc(N(C)C)cc3oc-2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
THRB P10828 2/20 0.50
RECQL P46063 2/20 0.50
BLM P54132 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
P2RY6 Q15077 1/20 0.43
ABCB1 P08183 1/20 0.43
FTO Q9C0B1 2/20 0.42
USP2 O75604 5/20 0.41
ATM Q13315 2/20 0.41
CFTR P13569 1/20 0.41
PAX8 Q06710 1/20 0.41
GOPC Q9HD26 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 3/20 0.40
KDM4E B2RXH2 2/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19520078 1.00 MEN1 (0.50) MEN1KMT2ATHRBRECQLBLM
SCHEMBL14064053 0.89 MEN1 (0.48) MEN1KMT2ATHRBRECQLBLM
SCHEMBL17777839 0.89 P2RY6 (0.48) MEN1KMT2ATHRBRECQLBLM
SCHEMBL14415041 0.89 P2RY6 (0.48) MEN1KMT2ATHRBRECQLBLM
SCHEMBL14383859 0.87 P2RY6 (0.47) MEN1KMT2ATHRBRECQLBLM
SCHEMBL14611311 0.85 ABCB1 (0.58) MEN1KMT2ATHRBRECQLBLM
SCHEMBL13848619 0.85 ABCB1 (0.58) MEN1KMT2ATHRBRECQLBLM
SCHEMBL15336458 0.85 P2RY6 (0.45) MEN1KMT2ATHRBRECQLBLM
Tetramethylrhodamine SCHEMBL2054818 0.84 MEN1 (0.71) MEN1KMT2ATHRBRECQLBLM
SCHEMBL18133212 0.84 MEN1 (0.69) MEN1KMT2ATHRBRECQLBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140336303-A1 Optical Element for Correcting Color Blindness NITTO DENKO CORPORATION (JP) 2014-11-13 US disclosed
US-20140336303-A1 Optical Element for Correcting Color Blindness NITTO DENKO CORPORATION (JP) 2014-11-13 US disclosed
EP-2594290-A1 Selective imaging of actin in live native cells Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2013-05-22 EP disclosed