Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14077551 | 0.93 | MEN1 (0.40) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL15100483 | 0.91 | TGM2 (0.42) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL17517217 | 0.91 | TGM2 (0.42) | MEN1THRBRECQLBLMKMT2A | |
| Hydrochloric Acid SCHEMBL11336327 | 0.91 | TGM2 (0.42) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL14192857 | 0.90 | ABCB1 (0.54) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL14597230 | 0.90 | P2RY6 (0.48) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL13577577 | 0.90 | P2RY6 (0.48) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL19520078 | 0.89 | MEN1 (0.50) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL14959448 | 0.89 | MEN1 (0.50) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL14192859 | 0.89 | ABCB1 (0.44) | MEN1THRBRECQLBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423122-B2 | N-terminal and C-terminal markers in nascent proteins | AMBERGEN, INC. | 2008-09-09 | — | — | US | disclosed |
| US-7312060-B2 | Methods for the detection, analysis and isolation of nascent proteins | AMBERGEN, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-20070003936-A1 | Methods for the detection of colorectal cancer | AMBERGEN, INC. | 2007-01-04 | — | — | US | disclosed |