Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.43 |
| ▸ | MMP13 | P45452 | 11/20 | 0.43 |
| ▸ | MMP9 | P14780 | 10/20 | 0.43 |
| ▸ | MMP3 | P08254 | 9/20 | 0.43 |
| ▸ | MMP7 | P09237 | 9/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328419 | 0.93 | MMP1 (0.49) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL778844 | 0.92 | MMP1 (0.48) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL14878449 | 0.90 | MMP1 (0.38) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL14878475 | 0.89 | MMP1 (0.37) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL12905399 | 0.88 | MMP1 (0.37) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL12905413 | 0.88 | MMP1 (0.36) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL918708 | 0.83 | MMP1 (0.54) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL328472 | 0.83 | MMP1 (0.54) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL919122 | 0.83 | MMP1 (0.53) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL919124 | 0.83 | MMP1 (0.53) | MMP1MMP13MMP9MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511488-B1 | HUMAN ADAM-10 INHIBITORS | SYMPHONY EVOLUTION INC (US) | 2013-05-22 | — | — | EP | disclosed |