SCHEMBL918708

SCHEMBL918708

COCCOC(=O)N1CCN(S(=O)(=O)c2cc(F)c(Oc3ccc(Cl)cc3)c(F)c2)C(C(=O)NO)C1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 19/20 0.54
MMP9 P14780 18/20 0.54
MMP3 P08254 17/20 0.54
MMP7 P09237 17/20 0.54
MMP13 P45452 16/20 0.54
ADAM17 P78536 2/20 0.48
MMP2 P08253 1/20 0.44
MMP8 P22894 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL328472 1.00 MMP1 (0.54) MMP1MMP9MMP3MMP7MMP13
SCHEMBL919124 0.99 MMP1 (0.53) MMP1MMP9MMP3MMP7MMP13
SCHEMBL919122 0.99 MMP1 (0.53) MMP1MMP9MMP3MMP7MMP13
SCHEMBL779102 0.94 MMP1 (0.55) MMP1MMP9MMP3MMP7MMP13
SCHEMBL779193 0.93 MMP1 (0.55) MMP1MMP9MMP3MMP7MMP13
SCHEMBL779159 0.92 MMP1 (0.57) MMP1MMP9MMP3MMP7MMP13
SCHEMBL12942841 0.92 MMP9 (0.44) MMP1MMP9MMP3MMP7MMP13
SCHEMBL778946 0.91 MMP1 (0.55) MMP1MMP9MMP3MMP7MMP13
SCHEMBL14878435 0.90 MMP9 (0.42) MMP1MMP9MMP3MMP7MMP13
SCHEMBL12905327 0.89 MMP9 (0.41) MMP1MMP9MMP3MMP7MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023196958-A2 TUMOR AND CANCER TARGETING COMPOUNDS ONCOLINX PHARMACEUTICALS (US) 2023-10-12 WO claimed
US-20260139061-A1 TREATMENT OF CANCER USING HUMANIZED ANTI-EGFRvIII CHIMERIC ANTIGEN RECEPTOR NOVARTIS AG (CH) 2026-05-21 US disclosed
US-12616733-B2 XBP1, CD138, and CS1 peptides, pharmaceutical compositions that include the peptides, and methods of using such peptides and compositions DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-05-05 US disclosed
US-12595260-B2 Stable heavy isotopes in amide functional groups and uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2026-04-07 US disclosed
EP-4714966-A2 CHIMERIC ENGULFMENT RECEPTOR MOLECULES AND METHODS OF USE Cero Therapeutics Holdings, Inc. (US) 2026-03-25 EP disclosed
US-20260077015-A1 CELLULAR IMMUNOTHERAPY COMPOSITIONS AND USES THEREOF CERO THERAPEUTICS HOLDINGS INC (US) 2026-03-19 US disclosed
EP-4376874-B1 CHIMERIC TIM4 RECEPTORS AND USES THEREOF CERO THERAPEUTICS HOLDINGS INC (US) 2026-03-04 EP disclosed
US-12559562-B2 Treatment of cancer using humanized anti-EGFRvIII chimeric antigen receptor NOVARTIS AG (CH) 2026-02-24 US disclosed
EP-3688032-B1 CHIMERIC ENGULFMENT RECEPTOR MOLECULES AND METHODS OF USE CERO THERAPEUTICS HOLDINGS INC (US) 2025-11-05 EP disclosed
US-20250250315-A1 CHIMERIC TIM4 RECEPTORS AND USES THEREOF CERO THERAPEUTICS HOLDINGS INC (US) 2025-08-07 US disclosed
EP-4038097-A1 CHIMERIC TIM4 RECEPTORS AND USES THEREOF Cero Therapeutics, Inc. (US) 2022-08-10 EP disclosed
WO-2022123316-A1 COMPOSITIONS OF GUANYLYL CYCLASE C (GCC) ANTIGEN BINDING AGENTS AND METHODS OF USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-06-16 WO disclosed
EP-4000619-A1 DOSAGE REGIMEN FOR AN ALPHA-ISOFORM SELECTIVE PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR Novartis AG (CH) 2022-05-25 EP disclosed
WO-2022098907-A1 METHODS AND COMPOSITIONS FOR TREATING FIBROTIC DISEASES MAX BioPharma, Inc. (US) 2022-05-12 WO disclosed
US-20220098273-A1 CHIMERIC ENGULFMENT RECEPTOR MOLECULES CERO THERAPEUTICS HOLDINGS, INC. 2022-03-31 US disclosed
EP-3519441-B1 CHIMERIC ENGULFMENT RECEPTOR MOLECULES CERO THERAPEUTICS INC (US) 2022-03-30 EP disclosed
WO-2022036285-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER WITH CHIMERIC TIM RECEPTORS IN COMBINATION WITH INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE CERO THERAPEUTICS, INC. (US) 2022-02-17 WO disclosed
WO-2022036287-A1 ANTI-CD72 CHIMERIC RECEPTORS AND USES THEREOF CERO THERAPEUTICS, INC. (US) 2022-02-17 WO disclosed
WO-2022036265-A1 CHIMERIC TIM RECEPTORS AND USES THEREOF CERO THERAPEUTICS, INC. (US) 2022-02-17 WO disclosed
US-20110003812-A1 Human Adam-10 Inhibitors SYMPHONY EVOLUTION, INC. (US) 2011-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003812-A1 Human Adam-10 Inhibitors ADAM10, MMP20, ADAM9 MMP1 13/4885MMP9 12/4885MMP3 30/4885
US-20260139061-A1 TREATMENT OF CANCER USING HUMANIZED ANTI-EGFRvIII CHIMERIC ANTIGEN RECEPTOR EGFR, ERBB2, HAVCR2 MMP1 4654/4885MMP9 4010/4885MMP3 3401/4885
US-12616733-B2 XBP1, CD138, and CS1 peptides, pharmaceutical compositions that include the peptides, and methods of using such peptides and compositions XBP1, MCL1, CD81 MMP1 3890/4885MMP9 4456/4885MMP3 3611/4885
US-12595260-B2 Stable heavy isotopes in amide functional groups and uses thereof SLC10A1, SLC9A1, SLC10A6 MMP1 918/4885MMP9 1779/4885MMP3 1961/4885
US-20260077015-A1 CELLULAR IMMUNOTHERAPY COMPOSITIONS AND USES THEREOF CD47, TNFSF10, CD2 MMP1 4152/4885MMP9 3328/4885MMP3 1633/4885
US-12559562-B2 Treatment of cancer using humanized anti-EGFRvIII chimeric antigen receptor EGFR, IGSF11, IGLV6-57 MMP1 4693/4885MMP9 4726/4885MMP3 4078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.