SCHEMBL14959643

SCHEMBL14959643

CCCN(CCC)c1cccc2c1CN([C@H](CCCNC(=O)OC(C)(C)C)c1ccc(OC)c(OC)c1)C2=O

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 18/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14959697 0.83 UTS2R (0.49) UTS2R
SCHEMBL8107524 0.83 UTS2R (0.75) UTS2R
SCHEMBL8118136 0.81 UTS2R (0.61) UTS2R
SCHEMBL14959696 0.79 UTS2R (0.49) UTS2R
SCHEMBL12157552 0.79 UTS2R (0.67) UTS2R
SCHEMBL2351529 0.75 UTS2R (0.76) UTS2R
SCHEMBL12174289 0.75 UTS2R (0.58) UTS2R
SCHEMBL14439749 0.74 UTS2R (0.70) UTS2R
SCHEMBL12157510 0.74 UTS2R (0.79) UTS2R
SCHEMBL8097607 0.74 UTS2R (0.52) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8445514-B2 Urotensin II receptor antagonists JANSSEN PHARMACEUTICA N.V. (BE) 2013-05-21 US disclosed