Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 16/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14959696 | 0.87 | UTS2R (0.49) | UTS2RTNF | |
| SCHEMBL14959643 | 0.83 | UTS2R (0.53) | UTS2R | |
| SCHEMBL2343966 | 0.79 | UTS2R (0.71) | UTS2R | |
| SCHEMBL2585279 | 0.78 | UTS2R (0.69) | UTS2R | |
| SCHEMBL8111219 | 0.77 | UTS2R (0.58) | UTS2R | |
| SCHEMBL2346366 | 0.75 | UTS2R (0.74) | UTS2R | |
| SCHEMBL12157524 | 0.75 | UTS2R (0.63) | UTS2R | |
| SCHEMBL8109910 | 0.74 | UTS2R (0.57) | UTS2R | |
| SCHEMBL2341361 | 0.72 | UTS2R (0.72) | UTS2R | |
| SCHEMBL8109705 | 0.72 | UTS2R (0.52) | UTS2RTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445514-B2 | Urotensin II receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-05-21 | — | — | US | disclosed |