Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049198 | 0.86 | — | — | |
| SCHEMBL11759094 | 0.86 | SLC2A1 (0.30) | — | |
| SCHEMBL13885338 | 0.85 | — | — | |
| SCHEMBL12333882 | 0.80 | GNAI3 (0.31) | PARP14 | |
| SCHEMBL20783150 | 0.76 | PHGDH (0.30) | — | |
| SCHEMBL17320920 | 0.76 | PHGDH (0.30) | — | |
| SCHEMBL575756 | 0.75 | — | — | |
| SCHEMBL5208686 | 0.75 | — | — | |
| SCHEMBL10881601 | 0.74 | SHBG (0.41) | PARP14 | |
| SCHEMBL776743 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019050850-A1 | BIGUANIDINE DERIVATIVES OF THERAPEUTIC AGENTS AND METHODS OF PREPARATION AND USE THEREOF | PRIMETIME LIFE SCIENCES, LLC (US) | 2019-03-14 | — | — | WO | disclosed |
| US-8445476-B2 | Carbacephem β-lactam antibiotics | ACHAOGEN, INC. (US) | 2013-05-21 | — | — | US | disclosed |