Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609987 | 0.88 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10TPMTGAA | |
| SCHEMBL7025073 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10TPMTGAA | |
| SCHEMBL28883701 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10TPMTGAA | |
| SCHEMBL8147306 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10TPMTGAA | |
| SCHEMBL1323406 | 0.77 | ALDH1A1 (0.68) | ALDH1A1KDM4EHSD17B10TPMTGAA | |
| SCHEMBL22061113 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10TPMTGAA | |
| SCHEMBL613131 | 0.76 | KDM4E (0.47) | ALDH1A1KDM4EHSD17B10TPMTGAA | |
| SCHEMBL8033045 | 0.75 | GAA (0.48) | ALDH1A1KDM4EHSD17B10TPMTGAA | |
| SCHEMBL8574112 | 0.75 | GAA (0.47) | ALDH1A1KDM4EHSD17B10TPMTGAA | |
| SCHEMBL7777887 | 0.75 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10TPMTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737831-B1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | PRANA BIOTECHNOLOGY LTD (AU) | 2013-05-22 | — | — | EP | disclosed |