Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.55 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24867413 | 0.85 | KDM4E (0.50) | FGFR1FGFR2ADORA3LMNAHSD17B10 | |
| SCHEMBL15452411 | 0.83 | ALDH1A1 (0.54) | LMNAPOLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9892909 | 0.83 | ADORA3 (0.56) | ADORA3LMNAL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL9891523 | 0.83 | POLB (0.50) | LMNAL3MBTL1POLBSMN1; SMN2ADORA1 | |
| SCHEMBL13872774 | 0.82 | ADORA2A (0.54) | ADORA3SMN1; SMN2ADORA1NPC1RAB9A | |
| SCHEMBL2257533 | 0.81 | POLB (0.43) | FGFR1FGFR2ADORA3LMNAL3MBTL1 | |
| SCHEMBL31741174 | 0.80 | KDM4E (0.54) | FGFR1FGFR2LMNAL3MBTL1POLB | |
| SCHEMBL16675463 | 0.78 | ADORA3 (0.47) | FGFR1FGFR2ADORA3LMNAL3MBTL1 | |
| SCHEMBL14647244 | 0.78 | KMT2A (0.54) | ADORA3LMNAPOLBSMN1; SMN2NPC1 | |
| SCHEMBL24827626 | 0.76 | SMN1; SMN2 (0.54) | ADORA3L3MBTL1POLBSMN1; SMN2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |
| EP-2217565-B1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |