Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709551 | 0.82 | MAPT (0.53) | KDM4EMAPTALDH1A1GAANPC1 | |
| SCHEMBL4403976 | 0.81 | ITGB1 (0.55) | KDM4EMAPTALDH1A1GAANPC1 | |
| SCHEMBL1205198 | 0.80 | SMN1; SMN2 (0.51) | KDM4EMAPTALDH1A1GAANPC1 | |
| SCHEMBL4401959 | 0.78 | ALDH1A1 (0.54) | KDM4EMAPTALDH1A1GAANPC1 | |
| SCHEMBL18052443 | 0.78 | NPC1 (0.53) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL5303474 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1GAAKMT2APOLB | |
| SCHEMBL5382777 | 0.76 | KMT2A (0.52) | MAPTALDH1A1GAANPC1RAB9A | |
| SCHEMBL9890035 | 0.76 | RXFP1 (0.46) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL25063097 | 0.75 | CYP2C19 (0.49) | KDM4EMAPTALDH1A1GAANPC1 | |
| SCHEMBL4399516 | 0.75 | HDAC1 (0.47) | KDM4EMAPTALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252584-B1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME INC (US) | 2016-12-07 | — | — | EP | disclosed |
| US-8445292-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2013-05-21 | — | — | US | disclosed |